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PMC	članci
PubMed	članci
NCBI	proteini

D-alanin-D-alaninska ligaza
D-alanin-D-alaninska ligaza
Identifikatori
EC broj	6.3.2.4
CAS broj	9023-63-6
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

D-alanin-D-alaninska ligaza (EC 6.3.2.4, MurE sintetaza, alanin:alanin ligaza (formira ADP), alanilalaninska sintetaza) je enzim sa sistematskim imenom D-alanin:D-alanin ligaza (formira ADP).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + 2 D-alanin

\rightleftharpoons

ADP + fosfat + D-alanil-D-alanin

Ovaj enzim učestvuje u sintezi peptida ćelijskog zida.

Reference

^ Ito, E. & Strominger, J.L. (1962). „Enzymatic synthesis of the peptide in bacterial uridine nucleotides. II. Enzymatic synthesis and addition of D-alanyl-D-alanine”. J. Biol. Chem. 237: 2696—2703.
^ Neuhaus, F.C. (1962). „Kinetic studies on D-Ala-D-Ala synthetase”. Fed. Proc. 21: 229—229.
^ van Heijenoort, J. (2001). „Recent advances in the formation of the bacterial peptidoglycan monomer unit”. Nat. Prod. Rep. 18: 503—519. PMID 11699883.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

D-alanine-D-alanine+ligase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Ito, E. & Strominger, J.L. (1962). „Enzymatic synthesis of the peptide in bacterial uridine nucleotides. II. Enzymatic synthesis and addition of D-alanyl-D-alanine”. J. Biol. Chem. 237: 2696—2703.

[2] Neuhaus, F.C. (1962). „Kinetic studies on D-Ala-D-Ala synthetase”. Fed. Proc. 21: 229—229.

[3] van Heijenoort, J. (2001). „Recent advances in the formation of the bacterial peptidoglycan monomer unit”. Nat. Prod. Rep. 18: 503—519. PMID 11699883.

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