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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Cikloartenol 24-C-metiltransferaza
Cikloartenol 24-C-metiltransferaza
Identifikatori
EC broj	2.1.1.142
CAS broj	50936-46-4
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Cikloartenol 24-C-metiltransferaza (EC 2.1.1.142, sterolna C-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:cikloartenol 24-C-metiltransferaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + cikloartenol

\rightleftharpoons

S-adenozil-L-homocistein + (24R)-24-metilcikloart-25-en-3beta-ol

S-adenozil-L-metionin metiluje Si stranu 24(25)-dvostruke veze eliminacijom atoma vodonika sa pro-Z metil grupe na C-25.

Reference

^ Mangla, A.T. & Nes, W.D. (2000). „Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition”. Bioorg. Med. Chem. 8: 925—36. PMID 10882005.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Cycloartenol+24-C-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Mangla, A.T. & Nes, W.D. (2000). „Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition”. Bioorg. Med. Chem. 8: 925—36. PMID 10882005.

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