PROFILPELAJAR.COM

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

3-metilkvercetin 7-O-metiltransferaza
3-metilkvercetin 7-O-metiltransferaza
Identifikatori
EC broj	2.1.1.82
CAS broj	97089-67-3
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

3-metilkvercetin 7-O-metiltransferaza (EC 2.1.1.82, flavonolna 7-O-metiltransferaza, flavonolna 7-metiltransferaza, 7-OMT, S-adenozil-L-metionin:3',4',5,7-tetrahidroksi-3-metoksiflavon 7-O-metiltransferaza, 3-metilkvercitinska 7-O-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:5,7,3',4'-tetrahidroksi-3-metoksiflavon 7-O-metiltransferaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + 5,7,3',4'-tetrahidroksi-3-metoksiflavon

\rightleftharpoons

S-adenozil-L-homocistein + 5,3',4'-trihidroksi-3,7-dimetoksiflavon

Ovaj enzim učestvuje zajedno sa EC 2.1.1.76, kvercetin 3-O-metiltransferazom i EC 2.1.1.83, 3,7-dimetilkvercetin 4'-O-metiltransferazom, u metilaciji kvercetina do 3,7,4'-trimetilkvercetina kod Chrysosplenium americanum. On ne deluje na flavone, dihidroflavonole, ili njihove glukozide.

Reference

^ De Luca, V. & Ibrahim, R.K. (1985). „Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4′-O-methyltransferases”. Arch. Biochem. Biophys. 238: 596—605. PMID 3994393.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

3-methylquercetin+7-O-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] De Luca, V. & Ibrahim, R.K. (1985). „Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4′-O-methyltransferases”. Arch. Biochem. Biophys. 238: 596—605. PMID 3994393.

[1]