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16S rRNK (guanin⁵²⁷-N⁷)-metiltransferaza
16S rRNK (guanin527-N7)-metiltransferaza
Identifikatori
EC broj	2.1.1.170
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

16S rRNK (guanin⁵²⁷-N⁷)-metiltransferaza (EC 2.1.1.170, metiltransferaza G ribozomalne RNK male podjedinice, 16S rRNK metiltransferaza RsmG, GidB, rsmG (gen)) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (guanin⁵²⁷-N⁷)-metiltransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + guanin⁵²⁷ u 16S rRNK

\rightleftharpoons

S-adenozil-L-homocistein + N⁷-metilguanin⁵²⁷ u 16S rRNK

Ovaj enzim specifično metiliše guanin⁵²⁷ u N⁷ poziciju u 16S rRNK.

Reference

^ Okamoto, S., Tamaru, A., Nakajima, C., Nishimura, K., Tanaka, Y., Tokuyama, S., Suzuki, Y. and Ochi, K. (2007). „Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria”. Mol. Microbiol. 63: 1096—1106. PMID 17238915.
^ Romanowski, M.J., Bonanno, J.B. and Burley, S.K. (2002). „Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold”. Proteins. 47: 563—567. PMID 12001236.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

16S+rRNA+(guanine527-N7)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Okamoto, S., Tamaru, A., Nakajima, C., Nishimura, K., Tanaka, Y., Tokuyama, S., Suzuki, Y. and Ochi, K. (2007). „Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria”. Mol. Microbiol. 63: 1096—1106. PMID 17238915.

[2] Romanowski, M.J., Bonanno, J.B. and Burley, S.K. (2002). „Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold”. Proteins. 47: 563—567. PMID 12001236.

[1]

[2]

16S rRNK (guanin527-N7)-metiltransferaza

Reference

Literatura

Spoljašnje veze