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16S rRNK (citozin¹⁴⁰⁷-C⁵)-metiltransferaza
16S rRNK (citozin1407-C5)-metiltransferaza
Identifikatori
EC broj	2.1.1.178
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

16S rRNK (citozin¹⁴⁰⁷-C⁵)-metiltransferaza (EC 2.1.1.178, RNK m5C metiltransferaza YebU, RsmF, YebU) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (citozin¹⁴⁰⁷-C⁵)-metiltransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + citozin¹⁴⁰⁷ u 16S rRNK

\rightleftharpoons

S-adenozil-L-homocistein + 5-metilcitozin¹⁴⁰⁷ u 16S rRNK

Ovaj enzim specifično metiliše citozin¹⁴⁰⁷ u C5 poziciji unutar 16S rRNK.

Reference

^ Andersen, N.M. & Douthwaite, S. (2006). „YebU is a m⁵C methyltransferase specific for 16 S rRNA nucleotide 1407”. J. Mol. Biol. 359: 777—786. PMID 16678201.
^ Hallberg, B.M., Ericsson, U.B., Johnson, K.A., Andersen, N.M., Douthwaite, S., Nordlund, P., Beuscher, A.E., 4th and Erlandsen, H. (2006). „The structure of the RNA m⁵C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain”. J. Mol. Biol. 360: 774—787. PMID 16793063.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

16S+rRNA+(cytosine1407-C5)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Andersen, N.M. & Douthwaite, S. (2006). „YebU is a m⁵C methyltransferase specific for 16 S rRNA nucleotide 1407”. J. Mol. Biol. 359: 777—786. PMID 16678201.

[2] Hallberg, B.M., Ericsson, U.B., Johnson, K.A., Andersen, N.M., Douthwaite, S., Nordlund, P., Beuscher, A.E., 4th and Erlandsen, H. (2006). „The structure of the RNA m⁵C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain”. J. Mol. Biol. 360: 774—787. PMID 16793063.

[1]

[2]

16S rRNK (citozin1407-C5)-metiltransferaza

Reference

Literatura

Spoljašnje veze