PROFILPELAJAR.COM

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

(Skp1-protein)-hidroksiprolin N-acetilglukozaminiltransferaza
(Skp1-protein)-hidroksiprolin N-acetilglukozaminiltransferaza
Identifikatori
EC broj	2.4.1.229
CAS broj	256531-81-4
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

(Skp1-protein)-hidroksiprolin N-acetilglukozaminiltransferaza (EC 2.4.1.229, Skp1-HyPro GlcNAc-transferaza, UDP-N-acetilglukozamin (GlcNAc):hidroksiprolin polipeptid GlcNAc-transferaza, UDP-GlcNAc:Skp1-hidroksiprolin GlcNAc-transferaza, UDP-GlcNAc:hidroksiprolin polipeptid GlcNAc-transferaza) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:(Skp1-protein)-hidroksiprolin N-acetil-D-glukozaminil-transferaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

UDP-N-acetilglukozamin + [Skp1-protein]-hidroksiprolin

\rightleftharpoons

UDP + [Skp1-protein]-O-(N-acetil-D-glukozaminil)hidroksiprolin

Za dejstvo ovog enzima je neophodan ditiotreitol i divalentni katjon.

Reference

^ van der Wel, H., Morris, H.R., Panico, M., Paxton, T., Dell, A., Kaplan, L. and West, C.M. (2002). „Molecular cloning and expression of a UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase that modifies Skp1 in the cytoplasm of Dictyostelium”. J. Biol. Chem. 277: 46328—46337. PMID 12244115.
^ Teng-umnuay, P., van der Wel, H. and West, C.M. (1999). „Identification of a UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase in the cytoplasm of Dictyostelium”. J. Biol. Chem. 274: 36392—36402. PMID 10593934.
^ West, C.M., van der Wel, H. and Gaucher, E.A. (2002). „Complex glycosylation of Skp1 in Dictyostelium: implications for the modification of other eukaryotic cytoplasmic and nuclear proteins”. Glycobiology. 12: 17—17. PMID 11886837.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

(Skp1-protein)-hydroxyproline+N-acetylglucosaminyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] van der Wel, H., Morris, H.R., Panico, M., Paxton, T., Dell, A., Kaplan, L. and West, C.M. (2002). „Molecular cloning and expression of a UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase that modifies Skp1 in the cytoplasm of Dictyostelium”. J. Biol. Chem. 277: 46328—46337. PMID 12244115.

[2] Teng-umnuay, P., van der Wel, H. and West, C.M. (1999). „Identification of a UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase in the cytoplasm of Dictyostelium”. J. Biol. Chem. 274: 36392—36402. PMID 10593934.

[3] West, C.M., van der Wel, H. and Gaucher, E.A. (2002). „Complex glycosylation of Skp1 in Dictyostelium: implications for the modification of other eukaryotic cytoplasmic and nuclear proteins”. Glycobiology. 12: 17—17. PMID 11886837.

[1]

[2]

[3]