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(Mijelin bazni protein)-arginin N-metiltransferaza
(Mijelin bazni protein)-arginin N-metiltransferaza
Identifikatori
EC broj	2.1.1.126
CAS broj	56214-31-4
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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NCBI	proteini

(Mijelin bazni protein)-arginin N-metiltransferaza (EC 2.1.1.126, mijelin bazno proteinska metilaza I, proteinska metilaza I, S-adenozil-L-metionin:(mijelin-bazni-protein)-arginin omega-N-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:(mijelinski-bazni-protein)-arginin N^omega-metiltransferaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + [mijelin bazni protein]-arginin

\rightleftharpoons

S-adenozil-L-homocistein + [mijelin bazni protein]-N^omega-metil-arginin

Enzim iz mozga sisara formira N^omega-monometil-, N^omega,N^omega-dimetil- i N^omega,N^omega^'-dimetil-argininske derivate.

Reference

^ Ghosh, S.K., Paik, W.K., Kim, S. (1988). „Purification and molecular identification of two protein methylases I from calf brain. Myelin basic protein and histone-specific enzyme”. J. Biol. Chem. 263: 19024—19033. PMID 2461933.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

(myelin+basic+protein)-arginine+N-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Ghosh, S.K., Paik, W.K., Kim, S. (1988). „Purification and molecular identification of two protein methylases I from calf brain. Myelin basic protein and histone-specific enzyme”. J. Biol. Chem. 263: 19024—19033. PMID 2461933.

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