N-hidroksiarilamin O-acetiltransferaza

N-hidroksiarilamin O-acetiltransferaza
Identifikatori
EC broj 2.3.1.118
CAS broj 100984-92-7
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

N-hidroksiarilamin O-acetiltransferaza (EC 2.3.1.118, arilhidroksamat N,O-acetiltransferaza, arilaminska N-acetiltransferaza, N-hidroksi-2-aminofluor-O-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:N-hidroksiarilamin O-acetiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

acetil-KoA + N-hidroksiarilamin KoA + N-acetoksiarilamin

Enzim iz jetre, za razliku od enzima iz bakterija, takođe može da katalizuje N-acetilaciju arilamina i N,O-acetilaciju arilhidroksamata.

Reference

  1. ↑ Saito, K., Shinohara, A. and Kamataki, T. (1986). „N-Hydroxyarylamine O-acetyltransferase in hamster liver: identity with arylhydroxamic acid N,O-acetyltransferase and arylamine N-acetyltransferase”. J. Biochem. (Tokyo) 99: 1689-1697. PMID 3745141. 

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