Feri-helat reduktaza (NADPH)

Feri-helat reduktaza (NADPH)
Identifikatori
EC broj 1.16.1.9
CAS broj 120720-17-4
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Feri-helat reduktaza (NADPH) (EC 1.16.1.9, feri helatna reduktaza, gvožđe helatna reduktaza, NADPH:Fe3+-EDTA reduktaza, NADPH-zavisna feri reduktaza, ZQJH (gen)) je enzim sa sistematskim imenom Fe(II):NADP+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

2 Fe(II) + 2 apo-siderofor + NADP+ + H+ 2 Fe(III)-siderofor + NADPH

Ovaj enzim sadrži FAD. Readkcija je katalizovana u reverznom smeru.

Reference

  1. ↑ Bamford, V.A., Armour, M., Mitchell, S.A., Cartron, M., Andrews, S.C. and Watson, K.A. (2008). „Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase”. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64: 792-796. PMID 18765906. 
  2. ↑ Wang, S., Wu, Y. and Outten, F.W. (2011). „Fur and the novel regulator YqjI control transcription of the ferric reductase gene yqjH in Escherichia coli”. J. Bacteriol. 193: 563-574. PMID 21097627. 
  3. ↑ Miethke, M., Hou, J. and Marahiel, M.A. (2011). „The Siderophore-Interacting Protein YqjH Acts as a Ferric Reductase in Different Iron Assimilation Pathways of Escherichia coli”. Biochemistry: -. PMID 22098718. 

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