1-Pirolin-4-hidroksi-2-karboksilatna deaminaza

1-Pirolin-4-hidroksi-2-karboksilatna deaminaza
Identifikatori
EC broj 3.5.4.22
CAS broj 9054-77-7
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

1-Pirolin-4-hidroksi-2-karboksilatna deaminaza (EC 3.5.4.22, HPC deaminaza) je enzim sa sistematskim imenom 1-pirolidin-4-hidroksi-2-karboksilat aminohidrolaza (deciklizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

1-pirolidin-4-hidroksi-2-karboksilat + H2O 2,5-dioksopentanoat + NH3

Reference

  1. ↑ Singh, R.M.M. and Adams, E. (1965). „Enzymatic deamination of Δ1-pyrroline-4-hydroxy-2-carboxylate to 2,5-dioxovalerate (α-ketoglutaric semialdehyde)”. J. Biol. Chem. 240: 4344-4351. PMID 5845838. 
  2. ↑ Singh, R.M.M. and Adams, E. (1965). „Isolation and identification of 2,5-dioxovalerate, an intermediate in the bacterial oxidation of hydroxyproline”. J. Biol. Chem. 240: 4352-4356. PMID 5845839. 

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