(Citohrom c)-lizin N-metiltransferaza

(Citohrom c)-lizin N-metiltransferaza
Identifikatori
EC broj 2.1.1.59
CAS broj 82047-78-7
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

(Citohrom c)-lizin N-metiltransferaza (EC 2.1.1.59, citohrom c (lizin) metiltransferaza, citohrom c metiltransferaza, citohrom c-specifična proteinska metilaza III, citohrom c-specifična protein-lizinska metiltransferaza, S-adenozil-L-metionin:(citohrom c)-L-lizin 6-N-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:(citohrom c)-L-lizin N6-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + citohrom c-L-lizin S-adenozil-L-homocistein + [citohrom c]-N6-metil-L-lizin

Ovaj enzim pripada grupi metilacinih proteina, cf. EC 2.1.1.43, histon-lizin N-metiltransferaza i EC 2.1.1.60, kalmodulin-lizin N-metiltransferaza.

Reference

  1. Durban, E., Nochumson, S., Kim, S. and Paik, W.K. (1978). „Cytochrome c-specific protein-lysine methyltransferase from Neurospora crassa. Purification, characterization, and substrate requirements”. J. Biol. Chem. 253: 1427-1435. PMID 203592. 
  2. Nochumson, S., Durban, E., Sangduk, K. and Paik, W.K. (1977). „Cytochrome c-specific protein methylase III from Neurospora crassa. Biochem. J. 165: 11-18. PMID 196592. 
  3. Valentine, J. and Pettigrew, G.W. (1982). „A cytochrome c methyltransferase from Crithidia oncopelti”. Biochem. J. 201: 329-338. PMID 6282265. 

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