Обратная мутация

Обра́тная мута́ция, или реверси́вная мута́ция[1] (от лат. reversus — обратный и лат. mutatio — изменение) — мутация, восстанавливающая дикий фенотип, снимая действие прямой мутации, инактивировавшей ген[2]. Таким образом, в отличие от супрессорной мутации, влияющей только на фенотип, обратная мутация восстанавливает исходный генотип, а следовательно, и фенотип[3]. Различают два типа обратных мутаций:

  • истинная обратная мутация восстанавливает исходную последовательность нуклеотидов.
  • вторичная обратная мутация компенсирует эффект прямой мутации в другой части гена[2].

Примечания

  1. ↑ Биология человека: реверсивная мутация. Дата обращения: 14 апреля 2013. Архивировано 2 апреля 2013 года.
  2. ↑ 1 2 обратная мутация // Молекулярная биология и генетика. Толковый словарь: обратная мутация.
  3. ↑ Генетическая изменчивость микроорганизмов. Дата обращения: 14 апреля 2013. Архивировано из оригинала 13 декабря 2012 года.

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