Zaleplona

Zaleplona Alerta sobre risco à saúde


Nome IUPAC	N-(3-(3-cyanopyrazolo[1,5-a] pyrimidin-7-yl)phenyl)-N-ethylacetamide
Identificadores
Número CAS	151319-34-5
PubChem	5719
DrugBank	DB00962
KEGG	D00530
ChEBI	10102
Código ATC	N05CF03
DCB n°	09231
Primeiro nome comercial ou de referência	Sonata, Starnoc, Andante
Propriedades
Fórmula química	C₁₇H₁₅N₅O
Massa molar	305.33 g mol^-1
Farmacologia
Biodisponibilidade	30% (oral)^[1]
Via(s) de administração	Oral
Metabolismo	Hepático aldehyde oxidase (91%), CYP3A4 (9%)^[2]
Excreção	Renal
Classificação legal	Class C (UK) Schedule IV (US)
Página de dados suplementares
Estrutura e propriedades	n, ε_r, etc.
Dados termodinâmicos	Phase behaviour Solid, liquid, gas
Dados espectrais	UV, IV, RMN, EM
Exceto onde denotado, os dados referem-se a materiais sob condições normais de temperatura e pressão Referências e avisos gerais sobre esta caixa. Alerta sobre risco à saúde.

A zaleplona é um fármaco hipnótico da classe dos não benzodiazepínicos indicado no tratamento a curto prazo de insônias de diferentes tipos.^[3]

Referências

↑ Rosen AS, Fournié P, Darwish M, Danjou P, Troy SM (Abril 1999). «Zaleplon pharmacokinetics and absolute bioavailability». Biopharmaceutics & Drug Disposition. 20 (3): 171–175. PMID 10211871. doi:10.1002/(sici)1099-081x(199904)20:3<171::aid-bdd169>3.0.co;2-k
↑ «20859 S009, 011 FDA Approved Labeling Text 12.10.07» (PDF). FDA. Consultado em 21 de março de 2023
↑ «PDAMED-ZALEPLONA». Consultado em 13 de março de 2009. Arquivado do original em 21 de novembro de 2008

Este artigo sobre fármacos é um esboço. Você pode ajudar a Wikipédia expandindo-o.

Identificadores	ATC: N05CF03 CAS: 151319-34-5 ChEBI: 10102 ChEMBL: CHEMBL1521 ChemSpider: 5517 DrugBank: DB00962 DTXSID: DTXSID5023748 ECHA: 100.126.674 HMDB: HMDB0015097 IUPHAR: 4345 KEGG: C07484 MeSH: C085665 NDF-RT: N0000148625 PubChem: 5719 RxNorm: 74667 UMLS: C0251504 UNII: S62U433RMH

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