Acepromazina

Acepromazina
Alerta sobre risco à saúde
Nome IUPAC 1-{10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethanone
Identificadores
Número CAS 61-00-7
PubChem 6077
DrugBank DB01614
ChemSpider 5852
Código ATC N05AA04
SMILES
InChI
1/C19H22N2OS/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19/h4-5,7-10,13H,6,11-12H2,1-3H3
Propriedades
Fórmula química C19H22N2OS
Massa molar 326.45 g mol-1
Farmacologia
Biodisponibilidade 6.6L/kg, alto volume de distribuição
Via(s) de administração intravenoso, intramuscular, oral
Meia-vida biológica 3 horas em cavalos
Excreção encontrado na urina equina até 96 horas depois da administração
Classificação legal



{{{legal_status}}}

Página de dados suplementares
Estrutura e propriedades n, εr, etc.
Dados termodinâmicos Phase behaviour
Solid, liquid, gas
Dados espectrais UV, IV, RMN, EM
Exceto onde denotado, os dados referem-se a
materiais sob condições normais de temperatura e pressão
Referências e avisos gerais sobre esta caixa.
Alerta sobre risco à saúde.

Acepromazina ou acetilpromazina é um fármaco utilizado por veterinários como um tranqüilizante fenotiazínico produzindo depressão no sistema nervoso com supressão do sistema nervoso simpático. Dessa forma, age como um potente agente tranquilizante em cães e gatos.

Potencializa outras drogas analgésicas,[1] porém não é um analgésico propriamente dito, porém estudos recentes sugerem que a acepromazina age como analgésico em gatos, principalmente no uso em protocolos de tratamento de doenças que causam cólica, ou na castração de fêmeas, tendo em vista que a analgesia descoberta nessa espécie é principalmente muscular e visceral. Já foi comprovado que em anestesia, a tranquilização feita com acepromazina no pré-cirúrgico otimiza a ação dos medicamentos anestésicos gerais, sendo assim menor quantidade de fármacos será utilizada para os procedimentos. Não é aconselhado em casos de disfunção hepática, pois a detoxicação dessa droga ocorre no fígado. Também não é aconselhada em casos de envenenamento por organofosforados, choque e epilepsia.

Pode não funcionar como desejado em animais extremamente agressivos. Corre-se também o risco de uma hipotensão pela administração de acepromazina, causando colapso cardio-vascular. O uso deste fármaco deve ser feito apenas sob supervisão de um médico veterinário, assim como a dose a ser utilizada. A administração de dose incorreta pode levar o animal à morte, tendo em vista seu poder de depressão do sistema nervoso central.

Referências

  1. ↑ «Descrição do produto na página de um fabricante». Consultado em 13 de abril de 2009 

Ligações externas


Ícone de esboço Este artigo sobre uma droga é um esboço. Você pode ajudar a Wikipédia expandindo-o.

Read other articles:

Pegadaian (perusahaan)

Ada usul agar Direktur Utama PT Pegadaian digabungkan ke artikel ini. (Diskusikan) Untuk kegunaan lain, lihat gadai dan Rumah gadai. PT PegadaianKantor pusat di JakartaJenisPerseroan terbatasIndustriJasa keuanganDidirikan1 April 1901; 122 tahun lalu (1901-04-01)KantorpusatJakarta Pusat, DKI JakartaWilayah operasiIndonesiaTokohkunciDamar Latri Setiawan[1](Direktur Utama)Loto Srinaita Ginting[2](Komisaris Utama)MerekKCAKrasidaG-LabKreasiKresnaMuliaEmaskuThe GadeGaleri 24Jas...

 

Batu Zayit

Gambar dari inskripsi pada Batu Zayit. Batu Zayit (Inggris: Zayit Stone) adalah sebuat batu kapur besar seberat 17.3 kg (38 pounds) yang ditemukan dalam ekskavasi di Tel Zayit (Zeitah) di Lembah Guvrin (Guvrin Valley), sekitar 35 mil di sebelah barat daya kota Yerusalem), pada tahun 2005. Bagian yang rata dari batu tersebut ditulisi dengan seluruh urutan abjad Ibrani Kuno (Paleo-Hebrew abecedarium). Baris pertama memuat 18 huruf (alef sampai tsadi), sedangkan baris kedua memuat 4 hur...

 

Black Dog: Being A Teacher

Black Dog: Being A TeacherPoster promosiHangul블랙독 GenreDramaPembuatStudio DragonDitulis olehPark Joo-yunSutradaraHwang Joon-hyeokPemeranSeo Hyun-jinRa Mi-ranHa JoonNegara asalKorea SelatanBahasa asliKoreaJmlh. episode16ProduksiPengaturan kameraSingle-cameraRumah produksiUrban WorksDistributortvNRilis asliJaringantvNFormat gambar1080i (HDTV)Format audioDolby DigitalRilis16 Desember 2019 (2019-12-16) –4 Februari 2020 (2020-2-4) Black Dog: Being A Teacher (Hangul:...

Abruzzo

Abruzzo—  Vùng của Ý  — Hiệu kỳHuy hiệuAbruzzoQuốc giaÝThủ phủL'AquilaChính quyền • Thủ hiếnLuciano D'Alfonso (Dân chủ)Diện tích • Tổng cộng10.763 km2 (4,156 mi2)Dân số (ngày 30 tháng 10 năm 2012) • Tổng cộng1.307.919 • Mật độ120/km2 (310/mi2)Múi giờCET (UTC+1) • Mùa hè (DST)CEST (UTC+2)Mã ISO ...

 

شارل ألبير غوبا

شارل ألبير غوبا (بالفرنسية: Charles Albert Gobat)‏  معلومات شخصية الميلاد 21 مايو 1843(1843-05-21) الوفاة 16 مارس 1914 (70 سنة)برن مواطنة سويسرا  مناصب عضو مجلس الولايات السويسري   عضو خلال الفترة10 مارس 1884  – 30 نوفمبر 1890  الدائرة الإنتخابية كانتون برن  عضو المجلس الوطني السويسري[...

 

Gouvernement Crispi I

Cet article est une ébauche concernant la politique et l’Italie. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Gouvernement Crispi I(it) Governo Crispi I Royaume d'Italie Données clés Président du Conseil Francesco Crispi Formation 29 juillet 1887 Fin 9 mars 1889 Durée 1 an, 7 mois et 8 jours Composition initiale Coalition Gauche historique Depretis VIII Crispi II modifier - modifier le c...

The Adventures of Robin Hood

Halaman ini berisi artikel tentang film tahun 1938. Untuk penggunaan lain, lihat The Adventures of Robin Hood (disambiguasi). The Adventures of Robin HoodSampul DVDSutradara Michael Curtiz William Keighley Produser Hal B. Wallis Henry Blanke Skenario Norman Reilly Raine Seton I. Miller Rowland Leigh Pemeran Errol Flynn Olivia de Havilland Basil Rathbone Claude Rains Penata musik Erich Wolfgang Korngold Sinematografer Tony Gaudio Sol Polito W. Howard Greene (Technicolor photo) Natalie Ka...

 

Cilician pirates

Generic term used for all pirates of the Mediterranean Sea in the 2nd and 1st century BC Julius Caesar taken captive by Cilician pirates (Henri De Montaut, 1865) Cilician pirates dominated the Mediterranean Sea from the 2nd century BC until their suppression by Pompey in 67–66 BC. Because there were notorious pirate strongholds in Cilicia, on the southern coast of Asia Minor (modern-day Turkey), the term Cilician was long used to generically refer to any pirates in the Mediterranean. Rise o...

 

Sylvia Poggioli

American journalist Sylvia PoggioliBorn (1946-05-19) May 19, 1946 (age 77)Providence, Rhode Island, U.S.Alma materHarvard CollegeOccupationNPR correspondentSpouse Piero Benetazzo ​(died 2015)​ParentRenato Poggioli (father) Sylvia Poggioli (/ˈsɪlviə pəˈdʒoʊli/ SIL-vee-ə pə-JOH-lee, Italian: [ˈsilvja podˈdʒɔːli]; born 19 May 1946)[1] is a retired American radio reporter best known for her work with National Public Radio. She ...

Wilhelm Koppe

German Nazi, SS and police leader, SS-Obergruppenführer Wilhelm Koppe Karl Heinrich Wilhelm Koppe (15 June 1896 – 2 July 1975) was a German Nazi commander (Höhere SS und Polizeiführer (HSSPF), SS-Obergruppenführer). He was responsible for numerous atrocities against Poles and Jews in Reichsgau Wartheland and the General Government during the German occupation of Poland in World War II. Biography Koppe was born in Hildesheim near Hanover. He fought in the First World War. During the inte...

 

Neuromuscular disease

Medical conditionNeuromuscular diseaseCongenital nemaline myopathy (neuromuscular disorder)SpecialtyNeurology, neuromuscular medicine, physical medicine and rehabilitationCausesAutoimmune disorders,[1] genetic disorders,[2] environmental factors[3]Diagnostic methodMuscle electrophysiology tests, genetic testingTreatmentDepends on the disorder; many currently have no cure[2] A neuromuscular disease is any disease affecting the peripheral nervous system (PNS), ...

 

Kibbutz Movement

Largest settlement movement for kibbutzim in Israel This article does not cite any sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Kibbutz Movement – news · newspapers · books · scholar · JSTOR (January 2018) (Learn how and when to remove this message) Headquarters of the Kibbutz Movement, Tel Aviv The Kibbutz Movement (Hebrew: התנועה הקיבוצי�...

Zollikon

Zollikon gemeinde de Suiza y ciudad de Suiza Escudo ZollikonLocalización de Zollikon en SuizaPaís  Suiza• Cantón  Zúrich• Distrito MeilenUbicación 47°20′32″N 8°34′42″E / 47.342222222222, 8.5783333333333• Altitud 473 mSuperficie 7,84 km²Población[1]​ 12 517 hab. (2014)• Densidad 1597 hab./km²Lengua AlemánCódigo postal 8702Sitio web Sitio oficial[editar datos en Wikidata] Zol...

 

I misteri di Silvestro e Titti

I misteri di Silvestro e Tittiserie TV d'animazione Logo originale Titolo orig.The Sylvester & Tweety Mysteries Lingua orig.inglese PaeseStati Uniti StudioWarner Bros. Television Animation ReteKids WB 1ª TV9 settembre 1995 – 13 dicembre 2002 Stagioni5 Episodi52 (completa) Durata ep.22 min Editore it.Warner Home Video (VHS) Rete it.Rai 2 1ª TV it.1996 – 2003 Episodi it.52 (completa) Durata ep.&...

 

Jim Cawley

American politician (born 1969) Jim Cawley32nd Lieutenant Governor of PennsylvaniaIn officeJanuary 18, 2011 – January 20, 2015GovernorTom CorbettPreceded byJoe ScarnatiSucceeded byMike StackMember of the Bucks County Board of CommissionersIn officeJanuary 4, 2005 – January 18, 2011Preceded byMike FitzpatrickSucceeded byRobert G. Loughery Personal detailsBorn (1969-06-22) June 22, 1969 (age 54)Bristol, Pennsylvania, U.S.Political partyRepublicanSpouseSuzanne CawleyCh...

Freedom

For other uses, see Freedom (disambiguation). Ability to act or change without constraint Four Freedoms, a series of 1943 paintings by Norman Rockwell honoring Franklin D. Roosevelt's Four Freedoms, meant to describe the freedoms for which allied nations fought in World War II. Part of a series onLiberalism Schools Classical Conservative Cultural Democratic Feminist Equity Green Internationalist Muscular National Neo Ordo Radical Religious Christian Catholic Islamic Jewish Secular Social Tech...

 

Demographics of Romania

Demographics of RomaniaPopulation pyramid of Romania as of 2021Population19,892,812 (2023)[1]Density83.4/km2 (216/sq mi)Growth rate 1.19% (2023)Birth rate 9.292 births/1,000 population (2023)Death rate 13.393 deaths/1,000 population (2023)Life expectancy 76.6 years (2023) • male 72.9 years • female 80.5 yearsFertility rate1.71 children born/woman (2022)[2]Infant mortality rate5.6 deaths/1,000 live births (2023)[3] [4]Net migra...

 

Hatboro station

HatboroGeneral informationLocation21 South Penn StreetHatboro, PennsylvaniaCoordinates40°10′32″N 75°06′11″W / 40.1756°N 75.1030°W / 40.1756; -75.1030Owned bySEPTALine(s)Warminster BranchPlatforms1 side platformTracks1ConstructionParking175 spacesAccessibleNoOther informationFare zone3HistoryOpened1871RebuiltDecember 1934–June 1, 1935[1][2]ElectrifiedJuly 26, 1931[3]Passengers2017500 boardings530 alightings(weekda...

Вулиця Соломії Крушельницької (Київ)

У Вікіпедії є статті про інші вулиці з такою назвою: Вулиця Соломії Крушельницької. Вулиця Соломії КрушельницькоїКиїв Місцевість ОсокоркиРайон ДарницькийНазва на честь С. А. КрушельницькоїКолишні назви вул. Нова, 2Загальні відомостіПротяжність 1,37 кмКоординати по�...

 

Musim VFL 1945

Musim Kejuaraan VFL 1945Skuat tim premier, Carlton FCTim peserta12PremiersCarlton (premiership ke-7)Minor premiersSouth Melbourne (minor premiership ke-6)Pertandingan124Penonton terbanyak62.986Medalis leading goalkickerFred Fanning (Melbourne)← 19441946 → Musim Victorian Football League 1945 adalah musim ke-49 dari penyelenggaraan VFL, kompetisi sepak bola menurut peraturan Australia. Juara (premier) edisi ini diraih oleh Carlton, sementara juara musim (minor premier) da...