Satoshi Ōmura
Satoshi Ōmura [satoɕi oːmu͍ɽa] (大村 智 Ōmura Satoshi ialah ahli biokimia Jepun. Beliau terkenal dengan penemuan dan perkembangan pelbagai farmaseutikal yang asalnya berlaku dalam mikroorganisma .[ 1] Hadiah Nobel dalam Fisiologi atau Perubatan bersama William C. Campbell dan Tu Youyou .[ 2] [ 3] [ 4] [ 5]
Penerbitan
Ōmura, S.; wai, A.; Hirano, A.; Nakagawa, A.; Awaya, J.; Tsuchiya, H.; Takahashi, Y.; Masuma, R. (1977). "A new alkaloid AM-2282 of Streptomyces origin: Fermentation, isolation and preliminary characterization". J. Antibiot . 30 (4): 275–282. doi :10.7164/antibiotics.30.275 . PMID 863788 . Burg, R. W.; Miller, B. M.; Baker, E. E.; Birnbaum, J.; Currie, S. A.; Hartman, R.; Kong, Y.-L.; Monaghan, R.; Olson, G.; Putter, I.; Tunac, J. B.; Wallick, H.; Stapley, E. O.; Oiwa, R.; Ōmura, S. (1979). "Avermectins, new family of potent anthelmintic agents: producing organism and fermentation" . Antimicrob. Agents Chemother . 15 (3): 61–367. doi :10.1128/AAC.15.3.361 . PMC 352666 PMID 464561 . Hopwood, D.A.; Malphatida, F.; Kieser, H.M.; Ikeda, J.; Juncan, J.; Fujii, B.A.M.; Rudd, H.; Floss, G.; Ōmura, S. (1984). "Production of 'hybrid' antibiotics by genetic engineering" . Nature . 314 (6012): 642–644. doi :10.1038/314642a0 . PMC 180355 PMID 3460518 . Ikeda, H.; Nonomiya, T.; Usami, M.; Ohta, T; Ōmura, S. (1999). "Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis" . Proc. Natl. Acad. Sci . 96 (17): 9509–9514. doi :10.1073/pnas.96.17.9509 . PMC 22239 PMID 10449723 . Hayashi, M.; Rho, M.-C.; Enomoto, A.; Fukami, A.; Kim, Y.-P.; Kikuchi, Y.; Sunazuka, T.; Hirose, T.; Komiyama, K.; Ōmura, S. (2002). "Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130" . Proc. Natl. Acad. Sci . 99 (21): 14728–14739. doi :10.1073/pnas.211433198 . PMC 59794 PMID 11572948 . Hirose, T.; Sunazuka, T.; Ōmura, S. (2010). "Recent development of two chitinase inhibitors, argifin and argadin, produced by soil microorganisms (Rev. article)" . Proc. Jpn. Acad . 86 (2): 85–102. doi :10.2183/pjab.86.85 . PMC 3417560 PMID 20154467 . Matoba, N.; Husk, A.S.; Barnett, B.W.; Pickel, M.M.; Arntzen, C.J.; Montefiori, D.C.; Takahashi, A.; Tanno, K; Omura, Satoshi; Cao, C.; Mooney, J.P.; Hanson, C.V.; Tanaka, H. (2010). "HIV-1 Neutralization Profile and Plant-Based Recombinant Expression of Actinohivin, an Env Glycan-Specific Lectin Devoid of T-Cell Mitogenic Activity" . PLoS ONE . 5 (6): e11143. doi :10.1371/journal.pone.0011143 . PMC 2886112 PMID 20559567 . Nakano, H.; Ōmura, S. (2009). "Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine (Review article)". J. Antibiot . 62 (1): 17–26. doi :10.1038/ja.2008.4 . PMID 19132059 . Ōmura, S. (2011). "Microbial metabolites: 45 years of wandering, wondering and discovering". Tetrahedron . 67 : 6420–6459. doi :10.1016/j.tet.2011.03.117 .
Rujukan
Pautan luar
1901–1925 1926–1950 1951–1975 1976–2000 2001–kini
Umum Perpustakaan negara Pangkalan data saintifik Lain-lain
