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Hyponatraemia sive hyponatriaemia (ICD-10 : E87.1) est in medicina minor (hypo- ) natrii concentratio (-natr(i)- ) in sanguine (-aemia )[ 1] et frequentissima electrolytorum perturbationum [ 2] . Symptomata multipliciter esse possunt. Haec perturbatio parvo valore (< 135 mmol/L) in sanguine aestimatur. Causae hyponatraemiae sunt, per exemplum, consumptio diureticorum (ut thiazidi ), aetas (senectus ), hypoglykaemia, diabetes mellitus , consumptio inhibitorum enzymi angiotensinum convertentes , oesophagitis, infectiones systematis urogenitalis .[ 3]
Correctio hyponatraemiae diligenter fienda est; si quae enim nimis cito peragatur, in cerebro myelinolysis pontina centralis periculosa oriatur.
Concentrationis nimis natrii vocatur hypernatraemia .
Physiologia
In corpore humano et pondere 70 chiliogrammatum circiter 100 g natrii insunt.[ 4] . Valor natrii normalis in sanguine est 135–145 mmol/l.
Hyponatraemia medicamentis causa
Consumptio non solum diureticorum (thiazidorum), sed etiam inhibitorum reabsorptionis serotonini selectivorum (SSRI ) atque Venlafaxini hyponatraemiam contrahere potest[ 5] .
Notae
↑ Williams D. M., Gallagher M., Handley J., Stephens J. W. (Iul 2016). "The clinical management of hyponatraemia". Postgraduate Medical Journal 92 (1089): 407–11
↑ Upadhyay A., Jaber B. L., Madias N. E. (Iul 2006). "Incidence and prevalence of hyponatremia" . American Journal of Medicine 119 (suppl 1) : S30-5
↑ Rastogi D., Pelter M. A., Deamer R. L. (Mar 2012). "Evaluations of Hospitalizations Associated With Thiazide-Associated Hyponatremia" . J Clin Hypertensio 14 : 158–64
↑ W. Kaim, B. Schwederski: Bioanorganische Chemie. 4. Auflage. Teubner, Wiesbaden 2005, ISBN 3-519-33505-0 . (Theodisce )
↑ Romero S., Pintor L., Serra M., Plana T., Navarro V., Gastó C., Goldstein B. (2007). "Syndrome of inappropriate secretion of antidiuretic hormone due to citalopram and venlafaxine" . General hospital psychiatry 29 (1): 81–4
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