프랑수아 자코브

프랑수아 자코브
François Jacob
1965년
1965년
출생 1920년 6월 17일(1920-06-17)[1]
프랑스 낭시
사망 2013년 4월 19일(2013-04-19)(92세)[1]
프랑스 파리
국적 프랑스
출신 학교 파리 대학교
주요 업적 오페론[2][3]
수상 Grand Prix Charles-Leopold Mayer(1962년)
노벨 생리학·의학상(1965년)
ForMemRS(1973년)[4]
한스 크레브스 경 메달(영어판)(1982년)
분야 병리학
유전학

프랑수아 자코브(프랑스어: François Jacob, ForMemRS[4], 1920년 6월 17일 ~ 2013년 4월 19일)는 프랑스의 병리학자, 유전학자이다. 1965년에 효소의 유전적 조절 작용과 바이러스 합성에 대한 연구로 앙드레 르보프, 자크 모노와 함께 노벨 생리학·의학상을 수상했다.[1][5][6][4]

수상 경력

회원

서적

  • Jacob, François; E. L. Wollman. Sexuality and the Genetics of Bacteria. Academic Press, 1961 OCLC 251900319
  • Jacob, François. The Possible & The Actual. Pantheon Books, 1982 ISBN 9780295958880
  • Jacob, François. The Statue Within: An Autobiography by, translated from the 1987 French edition by Franklin Philip. Basic Books, 1988. ISBN 978-0-465-08223-0; new edition: 9780879694760
  • Jacob, François. The Logic of Life. translated from the 1976 French edition by Princeton University Press, 1993 ISBN 0394472462
  • Jacob, François. Of Flies, Mice and Men, translated from the French edition and published by Harvard University Press, 1998 ISBN 9780674631113
  • Jacob, F.; Perrin, D.; Sánchez, C.; Monod, J.; Edelstein, S. (2005). “The operon: A group of genes with expression coordinated by an operator. C.R.Acad. Sci. Paris 250 (1960) 1727–1729”. 《Comptes rendus biologies》 328 (6): 514–520. doi:10.1016/j.crvi.2005.04.005. PMID 15999435. 
  • Ullmann, A.; Jacob, F.; Monod, J. (1968). “On the subunit structure of wild-type versus complemented beta-galactosidase of Escherichia coli”. 《Journal of Molecular Biology》 32 (1): 1–13. doi:10.1016/0022-2836(68)90140-X. PMID 4868117. 
  • Ullmann, A.; Jacob, F.; Monod, J. (1967). “Characterization by in vitro complementation of a peptide corresponding to an operator-proximal segment of the beta-galactosidase structural gene of Escherichia coli”. 《Journal of Molecular Biology》 24 (2): 339–343. doi:10.1016/0022-2836(67)90341-5. PMID 5339877. 
  • Ullmann, A.; Perrin, D.; Jacob, F.; Monod, J. (1965). “Identification, by in vitro complementation and purification, of a peptide fraction of Escherichia coli beta-galactosidase”. 《Journal of Molecular Biology》 12 (3): 918–923. doi:10.1016/S0022-2836(65)80338-2. PMID 4285628. 
  • Willson, C.; Perrin, D.; Cohn, M.; Jacob, F.; Monod, J. (1964). “Non-Inducible Mutants of the Regulator Gene in the "lactose" System of Escherichia Coli”. 《Journal of Molecular Biology》 8 (4): 582–592. doi:10.1016/S0022-2836(64)80013-9. PMID 14153528. 
  • Jacob, F.; Ullman, A.; Monod, J. (1964). “The Promotor, A Genetic Element Necessary to the Expression of an Operon”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 258: 3125–3128. PMID 14143651. 
  • Jacob, F.; Monod, J. (1964). “Biochemical and Genetic Mechanisms of Regulation in the Bacterial Cell”. 《Bulletin de la Societe de chimie biologique》 46: 1499–1532. PMID 14270538. 
  • Monod, J.; Changeux, J.; Jacob, F. (1963). “Allosteric proteins and cellular control systems”. 《Journal of Molecular Biology》 6 (4): 306–329. doi:10.1016/S0022-2836(63)80091-1. PMID 13936070. 
  • Jacob, F.; Sussman, R.; Monod, J. (1962). “On the nature of the repressor ensuring the immunity of lysogenic bacteria”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 254: 4214–4216. PMID 14036499. 
  • Jacob, F.; Monod, J. (1961). “Genetic regulatory mechanisms in the synthesis of proteins”. 《Journal of Molecular Biology》 3 (3): 318–356. doi:10.1016/S0022-2836(61)80072-7. PMID 13718526. 
  • Monod, J.; Jacob, F. (1961). “Teleonomic mechanisms in cellular metabolism, growth, and differentiation”. 《Cold Spring Harbor symposia on quantitative biology》 26: 389–401. doi:10.1101/sqb.1961.026.01.048. PMID 14475415. 
  • Perrin, D.; Jacob, F.; Monod, J. (1960). “Induced biosynthesis of a genetically modified protein not presenting affinity for the inductor”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 251: 155–157. PMID 13734531. 
  • Buttin, G.; Jacob, F.; Monod, J. (1960). “Constituent synthesis of galactokinase following the development of lambda bacteriophages in Escherichia coli K 12”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 250: 2471–2473. PMID 13806544. 
  • Jacob, F.; Perrin, D.; Sánchez, C.; Monod, J. (February 1960). “L'opéron : groupe de gènes à expression coordonnée par un opérateur” [Operon: a group of genes with the expression coordinated by an operator] (PDF). 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 (Facsimile version reprinted in 2005) 250 (6): 1727–1729. ISSN 0001-4036. PMID 14406329. 2016년 3월 4일에 원본 문서 (PDF)에서 보존된 문서. 2017년 10월 12일에 확인함. 
  • Jacob, F.; Monod, J. (1959). “Genes of structure and genes of regulation in the biosynthesis of proteins”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 249: 1282–1284. PMID 14406327. 
  • Pardee, A.; Jacob, F.; Monod, J. (1958). “The role of the inducible alleles and the constitutive alleles in the synthesis of beta-galactosidase in zygotes of Escherichia coli”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 246 (21): 3125–3128. PMID 13547552. 
  • Jacob, F.; Torriani, A.; Monod, J. (1951). “Effect of ultraviolet rays on the biosynthesis of galactosidase and on the multiplication of T2 bacteriophage in Escherichia coli”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 233 (20): 1230–1232. PMID 14905606. 

각주

  1. ↑ 가 나 다 Morange, Michel (2013). “François Jacob (1920–2013) French freedom fighter who helped to uncover how genes are regulated”. 《Nature》 497 (7450): 440. Bibcode:2013Natur.497..440M. doi:10.1038/497440a. PMID 23698437. 
  2. ↑ Jacob, F.; Perrin, D.; Sánchez, C.; Monod, J. (February 1960). “L'opéron : groupe de gènes à expression coordonnée par un opérateur” [Operon: a group of genes with the expression coordinated by an operator] (PDF). 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 (Facsimile version reprinted in 2005) 250 (6): 1727–1729. ISSN 0001-4036. PMID 14406329. 2016년 3월 4일에 원본 문서 (PDF)에서 보존된 문서. 2017년 10월 12일에 확인함. 
  3. ↑ Jacob, F. O. (2011). “The Birth of the Operon”. 《Science》 332 (6031): 767–767. Bibcode:2011Sci...332..767J. doi:10.1126/science.1207943. PMID 21566161. 
  4. ↑ 가 나 다 라 Morange, Michel (2017). “François Jacob. 17 June 1920 – 19 April 2013”. 《Biographical Memoirs of Fellows of the Royal Society》 (London: Royal Society): rsbm20160021. doi:10.1098/rsbm.2016.0021. ISSN 0080-4606. 
  5. ↑ Jacob, F.; Girard, M. (1998). “Andre Michel Lwoff. 8 May 1902–30 September 1994”. 《Biographical Memoirs of Fellows of the Royal Society》 44: 255–263. doi:10.1098/rsbm.1998.0017. ISSN 0080-4606. PMID 11623983. 
  6. ↑ “Nobel-winning biologist Francois Jacob dies at 92”. The Raw Story. 2014년 9월 9일에 원본 문서에서 보존된 문서. 2013년 4월 22일에 확인함. 

외부 링크

위키미디어 공용에 프랑수아 자코브 관련 미디어 분류가 있습니다.

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