脱髄した多発性硬化症の病変の顕微鏡写真。CD68を免疫染色しマクロファージが茶色に染まっている。原版の1
脱髄疾患(だつずいしっかん、demyelinating disease)とは神経疾患の一種で、有髄神経の髄鞘が障害されることで起こる疾患である。いったん形成された後に障害される疾患のことを言い、髄鞘形成が不完全なために起こる髄鞘形成不全疾患とは分けて考えられる。
有髄神経の周りには髄鞘と呼ばれるものが取り巻いている。これを形成する細胞は、中枢神経では乏突起膠細胞、末梢神経ではシュワン細胞である。この髄鞘があるために有髄神経では跳躍伝導を行うことができるため、これが障害されることで神経伝導速度が遅くなり、多彩な神経症状が引き起こされる。髄鞘を形成するグリア細胞は、神経に栄養を与えたり、保護したりする役割もあるため、髄鞘が障害されると神経細胞にダメージを与えてしまう[1]。
大きく分けて中枢神経系と末梢神経系の疾患がある。
脱髄しているか否かは病理学的な概念であるためT2WIにて高信号を認める病変として部位別にまとめる。
Chemical compound Not to be confused with Polyestradiol phosphate. Polyestriol phosphateSkeletal structure of polyestriol phosphate (top) and ball-and-stick model of estriol phosphate (one monomer of polyestriol phosphate) (bottom)Clinical dataTrade namesGynäsan, Klimadurin, TriodurinOther namesPE3P; SEP; Poly(estriol phosphate); Estriol phosphate polymer; Estriol polymer with phosphoric acidRoutes ofadministrationIntramuscular injectionDrug classEstrogen; Estrogen esterLegal statusLegal status…
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Johann August Nahl der Ältere (Jakob Emanuel Handmann, 1755) Standbild des Landgrafen Friedrich II. in Kassel, 1783 von Nahls Sohn vollendet Johann August Nahl, wegen seines gleichnamigen Sohnes Johann August Nahl der Ältere genannt (* 22. August 1710 in Berlin; † 22. Oktober 1781 in Kassel) war ein deutscher Bildhauer und Stuckateur. Er gehörte zu den bedeutenden Künstlern des Friderizianischen Rokoko. Inhaltsverzeichnis 1 Leben 1.1 Herkunft, Ausbildung 1.2 Straßburg 1.3 Berlin 1.4 Bern …
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SawooKecamatanPeta lokasi Kecamatan SawooNegara IndonesiaProvinsiJawa TimurKabupatenPonorogoPemerintahan • Camat-Populasi • Total53.340 jiwaKode Kemendagri35.02.05 Kode BPS3502050 Luas124,71 km²[1]Desa/kelurahan14 Sawoo adalah sebuah kecamatan di Kabupaten Ponorogo, Provinsi Jawa Timur, Indonesia. Kecamatan ini berjarak sekitar 25 kilometer[2] dari ibu kota Kabupaten Ponorogo ke arah tenggara. Pusat pemerintahannya berada di desa Sawoo. Batas wilayah…
This article may need to be rewritten to comply with Wikipedia's quality standards. You can help. The talk page may contain suggestions. (September 2020) DTACK Grounded was a computer hobbyist newsletter published from July 1981 to September 1985 by Hal W. Hardenberg.[1] Subtitled The Journal of Simple 68000 Systems, the newsletter was dedicated to the proposition that the Motorola 68000 CPU could be used to build simple, fast computers. In 1981 this was a revolutionary idea. This was be…
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