Sertaconazolo

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Questa voce sull'argomento farmaci è solo un abbozzo.

Contribuisci a migliorarla secondo le convenzioni di Wikipedia.

Sertaconazolo
Struttura chimica del sertaconazolo
Caratteristiche generali
Formula bruta o molecolare	C₂₀H₁₅Cl₃N₂OS
Massa molecolare (u)	437.77 g/mol
Numero CAS	99592-32-2
Codice ATC	D01AC14
PubChem	65863
DrugBank	DBDB01153
SMILES	`Clc1ccc (c(Cl)c1) C(OCc2c3cccc (Cl)c3sc2) Cn4ccnc4`
Indicazioni di sicurezza
Modifica dati su Wikidata · Manuale

Il sertaconazolo è un farmaco antimicotico della famiglia dei derivati imidazolici^[1].

Agisce bloccando la sintesi dell'ergosterolo nella cellula micotica inibendo l'enzima 14α-demetilasi^[1].

Stereochimica

Il sertaconazolo contiene uno stereocentro e consiste di due enantiomeri. Si utilizza come racemo, cioè una miscela in rapporto 1:1 delle forme ( R ) e ( S ):^[2]

Enantiomeri di sertaconazolo
CAS-Nummer: 583057-48-1	CAS-Nummer: 583057-51-6

Note

^ ^a ^b AJ. Carrillo-Muñoz, C. Tur-Tur; G. Giusiano; C. Marcos-Arias; E. Eraso; N. Jauregizar; G. Quindós, Sertaconazole: an antifungal agent for the topical treatment of superficial candidiasis., in Expert Rev Anti Infect Ther, vol. 11, n. 4, aprile 2013, pp. 347-58, DOI:10.1586/eri.13.17, PMID 23566144.
^ Rote Liste Service GmbH (Hrsg.): Rote Liste 2017 – Arzneimittelverzeichnis für Deutschland (einschließlich EU-Zulassungen und bestimmter Medizinprodukte). Rote Liste Service GmbH, Frankfurt/Main, 2017, Aufl. 57, ISBN 978-3-946057-10-9, S. 217.

Altri progetti

Wikimedia Commons contiene immagini o altri file su sertaconazolo

V · D · M

Cloruri

Inorganici

Cloruro ceroso • Cloruro d'ammonio • Cloruro d'argento • Cloruro di afnio(IV) • Tricloruro di americio • Cloruro d'alluminio • Tricloruro di antimonio • Pentacloruro di antimonio • Cloruro di bario • Cloruro di bromo • Cloruro di cadmio • Cloruro di calcio • Cloruro di cesio • Cloruro di cobalto • Tricloruro di cromo • Tricloruro di europio • Tricloruro di gadolinio • Tricloruro di itterbio • Cloruro di ittrio • Cloruro di litio • Tricloruro di lutezio • Cloruro di magnesio • Cloruro di nichel • Cloruro di tionitrosile • Tetracloruro di osmio • Cloruro di potassio • Cloruro di rubidio • Cloruro di sodio • Cloruro di stronzio • Cloruro di tiofosforile • Cloruro di zinco • Cloruro ferrico • Cloruro ferroso • Cloruro manganoso • Cloruro mercurico • Cloruro mercuroso • Tricloruro di praseodimio • Cloruro rameico • Cloruro rameoso • Cloruro stannico • Cloruro stannoso • Cloruro neodimico • Dicloruro di polonio • Tricloruro di uranio • Cloruro di idrogeno • Cloruro di renio(III) • Cloruro di renio(IV) • Cloruro di renio(V) • Cloruro di renio(VI) • Tricloruro di samario • Tricloruro di terbio

Organici

alchilici

Clorometano • Diclorometano • Triclorometano • Tetraclorometano • Cloroetano • 1,1-dicloroetano • 1,2-dicloroetano • Clorocicloesano • 3-cloro-1-propino • Cloruro di 5-dimetilamminonaftalen-1-solfonile • Cloruro di acetile • Cloruro di allile • Cloruro di benzalconio • Cloruro di benzendiazonio • Cloruro di polivinile • Cloruro di tetrafenilarsonio • Cloruro di vinile • 1,2-dicloro-1,2-difluoroetene •1,2-diclorotetrafluoroetano • 1,2-dicloro-1-(trifluorometossi)-1,2,2-trifluoroetano • Dicloruro di idrazina • Difenileneiodonio cloruro • Epicloridrina • Fluorenilmetilossicarbonil cloruro • 1,2,3,4-tetracloro-esafluorobutano

arilici

Clorobenzene • 1-cloro-2,4-dinitrobenzene • 7-cloro-4-nitrobenzofurazano • 1,2-diclorobenzene • 1,4-diclorobenzene • 1,2,4-triclorobenzene • 1,3,5-triclorobenzene • Pentaclorobenzene • Esaclorobenzene • Policlorobifenili

Analisi

Analisi dei cloruri

Portale Chimica

Portale Medicina

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