Bullatacina
| Bullatacina | |
|---|---|
 | |
| Nomi alternativi | |
| Asimicina, Rolliniastatina-1, Rolliniastatina-2 | |
| Caratteristiche generali | |
| Formula bruta o molecolare | C37H66O7 |
| Massa molecolare (u) | 622,921 |
| Numero CAS | |
| PubChem | 11124994 |
| SMILES | CCCCCCCCCCC(C1CCC(O1)C2CCC(O2)C(CCCCCCCCCCC(CC3=CC(OC3=O)C)O)O)O |
| Indicazioni di sicurezza | |
La bullatacina è una sostanza organica naturale appartenente alla classe delle acetogenine, isolata da piante appartenenti alla famiglia delle annonaceae, e dotata di attività antitumorale.[1]
Note
- ^ (EN) Hwa-Woei Chiha, Hui-Fen Chiub, Kung-Sung Tanga, Fang-Rong Changc, Yang-Chang Wu, Bullatacin, a potent antitumor annonaceous acetogenin, inhibits proliferation of human hepatocarcinoma cell line 2.2.15 by apoptosis induction, in Life Sciences, vol. 69, n. 11, 2001, pp. 1321-1331, DOI:10.1016/S0024-3205(01)01209-7.
Bibliografia
- (EN) H. Naito, E. Kawahara, K. Maruta, M. Maeda, S. Sasaki, The First Total Synthesis of (+)-Bullatacin, a Potent Antitumor Annonaceous Acetogenin, and (+)-(15,24)-bis-epi-Bullatacin, in J. Org. Chem., vol. 60, n. 14, 1995, pp. 4419–4427, DOI:10.1021/jo00119a019.
- (EN) Y.-H. Hui, J. K. Rupprecht, Y. M. Liu, J. E. Anderson, D. L. Smith, C.-J. Chang, J. L. McLaughlin, Bullatacin and Bullatacinone: Two Highly Potent Bioactive Acetogenins from Annona bullata, in J. Nat. Prod., vol. 52, n. 3, 1989, pp. 463–477, DOI:10.1021/np50063a002.
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