An haifi Salma Abu Deif a ranar 2 ga Fabrairun, shekarar 1993, a Alkahira, kasar Misira .Ta fara aikinta tana da shekaru 16, inda ta yi aiki a matsayin mai ba da labari a rediyo a Rehab FM . Ta sami digiri na farko a cikin Sadarwar Jama'a daga Jami'ar Misr International . A cikin shekarar 2017, ta fara yin wasan kwaikwayo a cikin wasan kwaikwayo na Halawt Al Dunia da La Tutafi" Alshams TV . cikin wannan shekarar, ta fara taka rawa a fim din Sheikh Jackson, wanda aka fara a bikin fina-finai na kasa da kasa na Toronto na 42 kuma shine gabatarwar Masar ga Kyautar Kwalejin don Mafi kyawun Fim na Harshen Ƙasashen waje na shekarar 2018.
Bayan sha'awarta a masana'antar kayan ado, Salma Abu Deif ta zama fuskar Maison Valentino a matsayin 'yar wasan kwaikwayo a Gabas ta Tsakiya a shekarar 2020. A cikin Shekarar 2023, ta yi aiki tare a karo na biyu tare da Maison Valentino .
A cikin 2022, Salma Abu Deif ta ƙaddamar da sabon alamar ELMA, alamar tufafin wanka na mata.[4][5]
