Acide dihydrofolique

Acide dihydrofolique

Structure de l'acide dihydrofolique
Identification
Synonymes

acide 7,8-dihydrofolique

No CAS 4033-27-6
No ECHA 100.116.435
PubChem 98792
ChEBI 15633
SMILES
InChI
Propriétés chimiques
Formule C19H21N7O6  [Isomères]
Masse molaire[1] 443,413 3 ± 0,019 9 g/mol
C 51,47 %, H 4,77 %, N 22,11 %, O 21,65 %,
Unités du SI et CNTP, sauf indication contraire.
modifier 

En biochimie, l’acide dihydrofolique est issu de l'acide folique, ou vitamine B9, par action de la folate réductase, et est le substrat de la dihydrofolate réductase pour produire le tétrahydrofolate, une coenzyme importante notamment dans la biosynthèse des bases nucléiques.

Dans le métabolisme animal, les dihydrofolates sont dégradés par l'enzyme dihydrofolate réductase (qui interagit avec le méthotrexate[2]).

Notes et références

  1. ↑ Masse molaire calculée d’après « Atomic weights of the elements 2007 », sur www.chem.qmul.ac.uk.
  2. ↑ Rajagopalan. P. T, Zhiquan Zhang, LynnMcCourt, Mary Dwyer, Stephen J.Benkovic, and Gordon G. Hammes, 2002. Interaction of dihydrofolatereductase with methotrexate: Ensembleand single-moleculekinetics. PNAS 99 (21): 13481–13486.

Voir aussi

Articles connexes

Liens externes

Bibliographie

v · m
Liposolubles
A
D
E
K
Hydrosolubles
B
C
v · m
Vitaminiques
Non vitaminiques
Oligoéléments

Read other articles:

The Man (Taylor Swift song)

2020 single by Taylor Swift The ManLive version coverSingle by Taylor Swiftfrom the album Lover ReleasedJanuary 27, 2020 (2020-01-27)Recorded2019Studio Electric Lady (New York City) Golden Age West (Auckland, New Zealand) Genre Electropop synth-pop Length3:10LabelRepublicSongwriter(s) Taylor Swift Joel Little Producer(s) Taylor Swift Joel Little Taylor Swift singles chronology Christmas Tree Farm (2019) The Man (2020) Cardigan (2020) Music videoThe Man on YouTube The Man is a s...

 

コルク

この記事は検証可能な参考文献や出典が全く示されていないか、不十分です。出典を追加して記事の信頼性向上にご協力ください。（このテンプレートの使い方）出典検索?: コルク – ニュース · 書籍 · スカラー · CiNii · J-STAGE · NDL · dlib.jp · ジャパンサーチ · TWL（2017年4月） コルクを打ち抜いて作った瓶の栓 コルク（木栓、�...

 

Transition metal formyl complex

Structure of the formyl complex CpRe(PPh3)(NO)CHO. Selected distances: dHC-O = 122.1, dHC-Re = 205.5, dON-Re = 177.7 pm.[1] In organometallic chemistry, a transition metal formyl complex is a metal complex containing one (usually) or more formyl (CHO) ligand. A subset of transition metal acyl complexes, formyl complexes can be viewed as metalla-aldehydes. A representative example is (CO)5ReCHO. The formyl is viewed as an X (pseudohalide) ligand. Metal formyls are proposed as intermedi...

New York State Department of State

Department of the New York state government Department of StateDepartment overviewJurisdictionNew YorkDepartment executiveRobert J. Rodriguez, Secretary of StateKey documentExecutive LawWebsitewww.dos.ny.gov The New York State Department of State (NYSDOS) is the department of the New York state government under the leadership of the Secretary of State of New York.[1] Its regulations are compiled in title 19 of the New York Codes, Rules and Regulations. Structure The NYSDOS includes th...

 

Jasper Francis Cropsey

American painter (1823–1900) Jasper Francis CropseyPortrait in oil at age 24 by Edward L. Mooney (1847)Born(1823-02-18)February 18, 1823Staten Island, New York, U.S.DiedJune 22, 1900(1900-06-22) (aged 77)Hastings-on-Hudson, New York, U.S.EducationHudson River SchoolKnown forLandscape artpainting Jasper Francis Cropsey (February 18, 1823 – June 22, 1900) was an American architect and artist. He is best known for his Hudson River School landscape paintings.[1] Early years ...

 

David Lean

British film director (1908–1991) For other people with the same name, see David Lean (disambiguation). SirDavid LeanCBELean in 1952Born(1908-03-25)25 March 1908Croydon, Surrey, EnglandDied16 April 1991(1991-04-16) (aged 83)Limehouse, London, EnglandResting placePutney Vale Cemetery, London, EnglandOccupationsFilm directorfilm producerscreenwriterfilm editorYears active1930–1991Spouses Isabel Lean ​ ​(m. 1930; div. 1936)​ Kay Walsh...

Wildlife of Iraq

Flora and fauna of Iraq The wildlife of Iraq includes its flora and fauna[1] and their natural habitats. Iraq has multiple biomes from mountainous region in the north to the wet marshlands along the Euphrates river. The western part of the country is mainly desert and some semi-arid regions. As of 2001, seven of Iraq's mammal species and 12 of its bird species were endangered. The endangered species include the northern bald ibis and Persian fallow deer. The Syrian wild ass is extinct...

 

Лятошинський Борис Миколайович

Борис Миколайович Лятошинський Борис Миколайович ЛятошинськийІм'я при народженні Борис Миколайович ЛятошинськийНародився 22 листопада (4 грудня) 1894[4][5]Житомир, Російська імперія[1]Помер 15 квітня 1968(1968-04-15)[1][2][…] (73 роки)Київ, Українська РСР, СРСР[1]...

 

Franchising

Practice of the right to use a firm's business model and brand for a prescribed period of time This article is about the business concept. For other uses, see Franchise. This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages) This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and ...

Badgerys Creek, New South Wales

This article is about the suburb. For the watercourse, see Badgerys Creek (New South Wales). For the airport, see Badgerys Creek Airport. For the electoral district, see Electoral district of Badgerys Creek. Suburb of Sydney, New South Wales, AustraliaBadgerys CreekSydney, New South WalesBadgerys Creek Road at Badgerys Creek ParkBadgerys CreekCoordinates33°52′47″S 150°45′08″E / 33.87972°S 150.75222°E / -33.87972; 150.75222Population168 (SAL 2021)[1...

 

سونيك ثري دي

سونيك 3D بلاست Sonic 3D Blast المطور سونيك تيم، ترافيلرز تيلز الناشر سيجا الموزع ستيم،  ونينتندو إي شوب  سلسلة اللعبة القنفذ سونيك  النظام ويندوز، بلاي ستيشن 3، إكس بوكس 360، سيجا ميجا درايف، سيجا ساترن، ماك أو أس، إكس بوكس لايف آركيد تاریخ الإصدار 1996 نوع اللعبة مغامرة النمط...

 

Elasmotherium

Elasmotherium Periode Miosen Akhir sampai Pleistosen Akhir, 7–0.039 jtyl PreЄ Є O S D C P T J K Pg N Rekonstruksi kerangka E. caucasicum, Azov History, Archaeology and Paleontology Museum-Reserve [fr]TaksonomiKelasMammaliaOrdoPerissodactylaFamiliRhinocerotidaeGenusElasmotherium J. Fischer, 1808[1] Tipe taksonomi †Elasmotherium sibiricum Tata namaSinonim takson Stereoceros Enigmatherium E. fischeri = E. sibiricum E. inexpectatum = E. caucasicum Spesies lain †E...

Eisenach

Eisenach Wartburg in Eisenach Lambang kebesaranLetak Eisenach NegaraJermanNegara bagianThüringenKreisDistrik perkotaanSubdivisions11Pemerintahan • MayorKatja WolfLuas • Total103,84 km2 (4,009 sq mi)Ketinggian220 m (720 ft)Populasi (2013-12-31)[1] • Total41.567 • Kepadatan4,0/km2 (10/sq mi)Zona waktuWET/WMPET (UTC+1/+2)Kode pos99817Kode area telepon03691Pelat kendaraanEASitus webwww.eisenach.de Untuk ko...

 

Angry Birds Star Wars

Cet article est une ébauche concernant le jeu vidéo. Vous pouvez partager vos connaissances en l’améliorant (comment ?) (voir l’aide à la rédaction). Angry Birds Star WarsDéveloppeur Rovio EntertainmentExient Entertainment (consoles)Éditeur Rovio EntertainmentActivision (consoles)Date de sortie 8 novembre 2012Franchise Angry Birds (d)Genre Artillerie, puzzleMode de jeu SoloPlate-forme Ordinateur(s) :Windows, MacConsole(s) :Wii, Wii U, PlayStation 3, PlayStation 4, X...

 

United States Secretary of Defense

Leader of the US armed forces following the president United States Secretary of DefenseSeal of the department[1]Flag of the secretary[2]IncumbentLloyd Austinsince January 22, 2021United States Department of DefenseOffice of the Secretary of DefenseStyleMr. Secretary (informal)The Honorable (formal)AbbreviationSecDefMember ofCabinetNational Security CouncilReports toPresident of the United StatesSeatThe Pentagon, Arlington County, VirginiaAppointerThe Presidentwith Senate...

Limited Edition Sportswear

Limited Edition SportswearCompany typePrivateIndustryTextileFounded2008FounderKris PillayHeadquarters71 Eagle StreetBrisbane, AustraliaArea servedOceania[1]ProductsSportswearOwnerKris PillayWebsitelesportswear.com Limited Edition Sportswear, generally styled as LE, is an Australian sportswear clothing company which was established in 2008 in the city of Brisbane in Queensland. It is owned by its founder, Kris Pillay.[2] Its slogan is Cultured by Choice Branded with Innovation...

 

Olaus Magnus

Swedish writer, cartographer, and prelate (1490–1557) The Most ReverendOlaus MagnusArchbishop of UppsalaPrimate of SwedenChurchRoman CatholicArchdioceseUppsalaAppointed4 June 1544Term ended1 August 1557PredecessorJohannes MagnusSuccessorLaurentius PetriPersonal detailsBornOlof MånssonOctober 1490Skänninge, SwedenDied1 August 1557 (aged 66)Rome, Papal StatesBuriedSanta Maria dell'Anima, RomeNationalitySwede Olaus Magnus (born Olof Månsson; October 1490 – 1 August 1557) was a Swedish wri...

 

Timothée Atouba

Timothée Atouba Informasi pribadiNama lengkap Timothée AtoubaTanggal lahir 17 Februari 1982 (umur 42)Tempat lahir Douala, KamerunTinggi 1,91 m (6 ft 3 in)Posisi bermain Bek kiriKarier junior1996–1999 Union DoualaKarier senior*Tahun Tim Tampil (Gol)1998–1999 Mineduc 24 (11)1999–2000 Union Douala 16 (4)2000–2002 Neuchâtel Xamax 46 (2)2002–2004 FC Basel 72 (3)2004–2005 Tottenham Hotspur 18 (1)2005–2009 Hamburger SV 83 (1)2009–2011 Ajax 11 (0)2012–2014 La...

Campionati europei di corsa campestre 2019

La neutralità di questa voce o sezione sull'argomento sport è stata messa in dubbio. Motivo: albo d'oro non corretto in quanto primi due squalificati per doping Per contribuire, correggi i toni enfatici o di parte e partecipa alla discussione. Non rimuovere questo avviso finché la disputa non è risolta. Segui i suggerimenti del progetto di riferimento. XXVI Campionato europeo di corsa campestre2019 European Cross Country Championships Competizione campionati europei di corsa campest...

 

Baudouin II dari Yerusalem

Baudouin IIRaja YerusalemGambaran Baudouin II dari abad ke-19.Berkuasa14 April 1118 – 21 Agustus 1131Penobatan14 April 1118PendahuluBaudouin IPenerusMelisendeKelahiran1060PrancisKematian21 Agustus 1131 (usia 70-71 tahun)YerusalemPemakamanGereja Makam Kudus, YerusalemPasanganMorfia dari MalatyaKeturunanMelisende dari YerusalemAlice dari AntiokhiaHodierna dari TripoliIoveta dari BetaniaWangsaWangsa RethelAyahHugues I dari RethelIbuMelisende dari Montlhéry (10??–1118) Baudouin II, juga dise...