Tolfenaamihappo

Tolfenaamihappo
Tolfenaamihappo
Systemaattinen (IUPAC) nimi
2-(3-kloori-2-metyylianilino)bentsoehappo
Tunnisteet
CAS-numero 13710-19-5
ATC-koodi M01AG02
PubChem CID 610479
Kemialliset tiedot
Kaava C14H12NClO2 
Moolimassa 261,704 g/mol
SMILES Etsi tietokannasta: eMolecules, PubChem
Fysikaaliset tiedot
Sulamispiste 207 °C
Farmakokineettiset tiedot
Hyötyosuus ?
Metabolia ?
Puoliintumisaika ?
Ekskreetio ?
Terapeuttiset näkökohdat
Raskauskategoria

?

Reseptiluokitus


Antotapa Oraalinen

Tolfenaamihappo on fenamaatteihin, kuten mefenaamihappokin, kuuluva, tulehdusta ja kipua lievittävä tulehduskipulääke.[1] Tolfenaamihappoa käytetään migreenin ja muiden päänsärkyjen hoitoon, hammassärkyyn, kuukautiskipuihin, nivelrikkoon, reumaattisiin ja muihin sidekudossairauksiin liittyvien kiputilojen hoitoon, luusto- ja lihasperäisiin kipuihin ja pinnalliseen laskimontukkotulehdukseen.[2] Hyvä teho on todettu eritoten kuukautiskipujen ja migreeninkivun lievityksessä.[1] Tolfenaamihappo tunnetaan kauppanimellä Clotam®.

Tolfenaamihapon vaikutus perustuu prostaglandiini- ja leukotrieenisynteesin estoon,[2] joka vaikuttaa edelleen kipua ja tulehdusta vähentävästi.

Tolfenaamihapon tehoa on tutkittu myös krapulaoireisiin. Sen havaittiin vähentävän merkittävästi päänsärkyä, pahoinvointia, oksentelua, ärsytystä, vapinaa, janoa ja suun kuivuutta.[3] Myös tolfenaamihapon tehottomuudesta krapulan hoidossa on näyttöä.[4]

Lähteet

Viitteet

  1. ↑ a b Koulu.M, Tuomisto.J et al, Farmakologia ja Toksikologia, 2007, 7.p s.323
  2. ↑ a b Clotam® 200 mg tabletti valmisteyhteenveto – Lääkelaitos[vanhentunut linkki]
  3. ↑ Kaivola S., Parantainen J., Österman T., Timonen H. Hangover headache and prostaglandins: prophylactic treatment with tolfenamic acid(englanniksi)
  4. ↑ Pittler MH, Verster JC, Ernst E: Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials. British Medical Journal, 2005;331, nro 331, s. 1515-8. Artikkelin verkkoversio.[vanhentunut linkki]

Aiheesta muualla

Kipulääkkeet eli analgeetit
Tulehduskipulääkkeetasetyylisalisyylihappo |

deksibuprofeeni | diflunisaali | diklofenaakki | etorikoksibi | flurbiprofeeni | ibuprofeeni | indometasiini | ketoprofeeni | ketorolaakki | mefenaamihappo | meloksikaami | naprokseeni | parekoksibi | piroksikaami | propyfenatsoni | rofekoksibi | selekoksibi | sulindaakki | tolfenaamihappo |

valdekoksibi
Opioiditalfentaniili |

buprenorfiini | dekstropropoksifeeni | dihydrokodeiini | endorfiini | etyylimorfiini | fentanyyli | heroiini | hydrokodoni | hydromorfoni | karfentaniili | kodeiini | metadoni | morfiini | nalbufiini | oksikodoni | oksimorfoni | pentatsosiini | petidiini | propoksifeeni | remifentaniili | sufentaniili | tebaiini | tilidiini |

tramadoli
Muutparasetamoli | kannabinoidit (lääkekannabis)

Read other articles:

TMTFA

Chemical compound TMTFA Names Preferred IUPAC name N,N,N-Trimethyl-3-(trifluoroacetyl)anilinium Identifiers CAS Number 156781-80-570311-60-3 (iodide salt) 3D model (JSmol) Interactive image ChemSpider 5291 PubChem CID 5492 UNII Z3M6Q7J3MZ Y CompTox Dashboard (EPA) DTXSID20274468 InChI InChI=1S/C11H13F3NO/c1-15(2,3)9-6-4-5-8(7-9)10(16)11(12,13)14/h4-7H,1-3H3/q+1Key: JIBZSTPMDKSJOX-UHFFFAOYSA-N SMILES C[N+](C)(C)C1=CC=CC(=C1)C(=O)C(F)(F)F Properties Chemical formula C11H13F3NO Mo...

 

Don't Ask, Don't Tell Repeal Act of 2010

2011 US federal law allowing LGBT people to openly serve in the military Don’t Ask, Don’t Tell Repeal Act of 2010Long titleA bill to provide for the repeal of the Department of Defense policy concerning homosexuality in the Armed Forces known as Don't Ask, Don't Tell.[1]NicknamesDADT RepealEnacted bythe 111th United States CongressEffectiveSeptember 20, 2011CitationsPublic law111–321Statutes at Large124 Stat. 3515, 3516 and 3517Legislative historyIntroduced in the House of ...

 

Gu (wadah)

Untuk kegunaan lain, lihat GU. Gu (wadah) Hanzi: 觚 Alih aksara Mandarin - Hanyu Pinyin: gū - Wade-Giles: ku1 Wadah gu dari Dinasti Shang terbuat dari perunggu dengan pigmen hitam. Gu adalah sejenis wadah perunggu ritual kuno Tiongkok yang diproduksi pada masa Dinasti Shang dan Dinasti Zhou (1600 - 256 Sebelum Masedhi). Wadah tersebut digunakan untuk minum anggur atau untuk sesajian. Gu memiliki bentuk yang tiggi dan ramping, dengan dasar yang sedikit melebar dan melangsing pada bagian teng...

Little, Brown and Company

Little, Brown and CompanyPerusahaan indukHachette Book Group USADidirikan1837; 186 tahun lalu (1837)PendiriCharles Coffin LittleJames BrownNegara asalAmerika Serikat/Britania RayaKantor pusatNew York CityImprintBack Bay Books; Mulholland Books; Jimmy Patterson Books; Little, Brown Spark; VoraciousSitus resmilittlebrown.com Little, Brown and Company perusahaan penerbit Amerika yang didirikan pada tahun 1837 oleh Charles Coffin Little dan rekannya, James Brown. Selama hampir dua abad, pene...

 

Anadyr (town)

For other uses, see Anadyr. Town in Chukotka Autonomous Okrug, RussiaAnadyr АнадырьTown[1] FlagCoat of armsLocation of Anadyr AnadyrLocation of AnadyrShow map of RussiaAnadyrAnadyr (Chukotka Autonomous Okrug)Show map of Chukotka Autonomous OkrugCoordinates: 64°44′N 177°31′E / 64.733°N 177.517°E / 64.733; 177.517CountryRussiaFederal subjectChukotka Autonomous Okrug[1]Founded1889[2]Town status since1965[2]Government •...

 

Cesena Football Club 2023-2024

Questa voce o sezione tratta di una competizione calcistica in corso. Le informazioni possono pertanto cambiare rapidamente con il progredire degli eventi. Se vuoi scrivere un articolo giornalistico sull'argomento, puoi farlo su Wikinotizie. Non aggiungere speculazioni alla voce. Voce principale: Cesena Football Club. Cesena FCStagione 2023-2024Sport calcio Squadra Cesena Allenatore Domenico Toscano All. in seconda Michele Napoli Presidente John Aiello Serie C1º (promosso in Serie B) C...

コルク

この記事は検証可能な参考文献や出典が全く示されていないか、不十分です。出典を追加して記事の信頼性向上にご協力ください。（このテンプレートの使い方）出典検索?: コルク – ニュース · 書籍 · スカラー · CiNii · J-STAGE · NDL · dlib.jp · ジャパンサーチ · TWL（2017年4月） コルクを打ち抜いて作った瓶の栓 コルク（木栓、�...

 

Mosque of Qani-Bay

Mosque in Cairo, Egypt Mosque of Qani-Bayمسجد قاني باي الرماحLocationLocationCairo, EgyptGeographic coordinates30°01′56″N 31°15′28″E / 30.0322°N 31.2579°E / 30.0322; 31.2579ArchitectureTypeMosque The Mosque of Qani-Bay is a mosque in Cairo, Egypt. The complex is named after Qani-Bay al-Sayfi, nicknamed al-Rammah, who was Grand Master of the Horse during the reign of Sultan al-Ghuri. It was built between AD 1503 and 1504 (AH 908) on a hill w...

 

Whitby-class frigate

Class of frigate of the Royal Navy HMS Tenby, a Whitby-class frigate, in Amsterdam, 1969 Class overview NameWhitby class Builders Vickers Armstrongs, Barrow Cammell Laird, Birkenhead Harland & Wolff, Belfast Operators  Royal Navy  Indian Navy  Royal New Zealand Navy Preceded byType 11 (never built) Succeeded byRothesay class In commission10 May 1956 (RN) – 31 August 1992 (IN)[1] Completed6 + 2 Indian General characteristics TypeFrigate Displacement 2,150 tons...

List of international presidential trips made by Donald Trump

This article is part of a series aboutDonald Trump Business and personal Business career The Trump Organization wealth tax returns Media career The Apprentice bibliography filmography Eponyms Family Foundation American football Golf Honors Public image in popular culture SNL parodies handshakes Legal affairs Sexual misconduct allegations Nicknames pseudonyms Racial views Comments on John McCain Conspiracy theories Residences Rhetoric 45th President of the United States Presidency timeline Tr...

 

Alden Ehrenreich

American actor Alden EhrenreichEhrenreich in 2018BornAlden Caleb Ehrenreich (1989-11-22) November 22, 1989 (age 34)Los Angeles, California, U.S.Alma materNew York UniversityOccupationActorYears active2005–present Alden Caleb Ehrenreich (/ˈɛərənraɪk/;[1] born November 22, 1989)[2] is an American actor. He began his career by appearing in the television series Supernatural (2005), and in Francis Ford Coppola's films Tetro (2009) and Twixt (2011). Following ...

 

Union Jack

Union JackRoyal Union FlagUnion FlagBendera Kesatuan Pemakaian Bendera nasional Perbandingan 3:5, 1:2 Dipakai 1801 Rancangan Gabungan Salib Santo Andreas, Salib Santo Patrick, dan Salib Santo Georgius Sebuah Bendera Union yang berkibaran Perkembangan bendera Union Jack Bendera Union Jack[1][2] atau nama resminya Union Flag (Bendera Kesatuan) adalah bendera nasional Britania Raya. Bendera ini juga memiliki status resmi atau semi-resmi di beberapa wilayah Persemakmuran lainnya;...

Sky Gilbert

This biography of a living person relies too much on references to primary sources. Please help by adding secondary or tertiary sources. Contentious material about living persons that is unsourced or poorly sourced must be removed immediately, especially if potentially libelous or harmful.Find sources: Sky Gilbert – news · newspapers · books · scholar · JSTOR (October 2018) (Learn how and when to remove this message) Canadian writer, actor, academic ,a...

 

Vladimir Romanov

Russian-Lithuanian businessman For the Soviet-Russian serial killer, see Vladimir Romanov (serial killer). For the Canadian murderer with the alias Vladimir Romanov, see Luka Magnotta In this name that follows Eastern Slavic naming customs, the patronymic is Nikolayevich and the family name is Romanov. This article needs to be updated. Please help update this article to reflect recent events or newly available information. (June 2013) Vladimir RomanovBorn (1947-06-15) 15 June 1947 (age...

 

معتمدية عقارب

معتمدية عقارب تقسيم إداري  البلد تونس  التقسيم الأعلى ولاية صفاقس  العاصمة عقارب  تعديل مصدري - تعديل   معتمدية عقارب إحدى معتمديات الجمهورية التونسية، تابعة لولاية صفاقس. تـــاريــخ الإحــداث : 1968. تبلغ مساحتها 735 كم مربع وتعداد سكانها سنة 2014 حوالي 40943 نسمة �...

Toronto Pearson International Airport

Airport in Malton, Ontario, Canada Toronto Airport, Pearson Airport and YYZ redirect here. For other airports in Toronto, see List of airports in the Greater Toronto Area. For the airfield in the United States, see Pearson Field. For the song by Canadian band Rush, see YYZ (song). Toronto Pearson International AirportIATA: YYZICAO: CYYZWMO: 71624SummaryAirport typePublicOwnerTransport CanadaOperatorGreater Toronto Airports AuthorityServesGreater TorontoLocationMalton, Mississauga, Ontario, Ca...

 

Serge Haroche

Questa voce sull'argomento fisici francesi è solo un abbozzo. Contribuisci a migliorarla secondo le convenzioni di Wikipedia. Serge Haroche (4 maggio 2009) Premio Nobel per la fisica 2012 Serge Haroche (Casablanca, 11 settembre 1944) è un fisico francese di origine marocchina, vincitore del Premio Nobel per la Fisica nel 2012, insieme allo statunitense David Wineland, per la scoperta riguardante i metodi sperimentali che hanno permesso la misurazione e la manipolazione dei sistemi...

 

Suhl

Suhl Armoiries Drapeau Administration Pays Allemagne Land  Thuringe Arrondissement(Landkreis) Suhl (ville-arrondissement) Nombre de quartiers(Ortsteile) 9 Bourgmestre(Bürgermeister) Jens Triebel Code postal 98501–98529 Code communal(Gemeindeschlüssel) 16 0 54 000 Indicatif téléphonique 03681 Immatriculation SHL Démographie Population 37 009 hab. (2022) Densité 261 hab./km2 Géographie Coordonnées 50° 36′ 00″ nord, 10° 42′ 00″...

Indulgentiarum Doctrina

1967 apostolic constitution by Pope Paul VI Part of a series on theCanon law of theCatholic Church Ius vigens (current law) 1983 Code of Canon Law Omnium in mentem Magnum principium Code of Canons of the Eastern Churches Ad tuendam fidem Ex corde Ecclesiae Indulgentiarum Doctrina Praedicate evangelium Veritatis gaudium Custom Matrimonial nullity trial reforms of Pope Francis Documents of the Second Vatican Council Christus Dominus Lumen gentium Optatam totius Orientalium ecclesiarum Presbyter...

 

Сен-Лезе

КоммунаСен-ЛезеSaint-Lézer Герб 43°22′11″ с. ш. 0°01′59″ в. д.HGЯO Страна  Франция Регион Юг — Пиренеи Департамент Верхние Пиренеи Кантон Вик-ан-Бигор Мэр Серж Жозеф(2014—2020) История и география Площадь 11,17 км² Высота центра 216–341 м Часовой пояс UTC+1:00, летом UTC+2:00 Население...