Struuma

Nainen, jolla on suurikokoinen struuma

Struuma (lat. struma) tarkoittaa kilpirauhasen suurentumaa.[1] Struumaan voi liittyä joko kilpirauhasen liika- tai vajaatoimintaa. Struumapotilaalla voi olla koholla tyrotropiini tai tyrotropiinireseptorin vasta-aine;[2] kummassakin tapauksessa kilpirauhanen stimuloituu voimakkaasti kasvamaan (hyperplasia).[3] Struumasta, johon liittyy liikatoimintaa, on käytetty Suomessa yleisesti nimitystä "myrkkystruuma".[4]

Struuman merkittävin syy on ollut jodin puutos (jodinpuutosstruuma eli endeeminen struuma[3]), minkä vuoksi ruokasuolaan alettiin lisätä jodia. Sairauteen on lääkitys, ja toisinaan turvaudutaan leikkaukseen.

Kaalikasveissa olevien glukosinolaattien hajoamistuotteiden on eläinkokeissa todettu aiheuttavan suurina pitoisuuksina esimerkiksi struumaa.[5]

Lähteet

  1. ↑ MOT Lääketiede 2.0
  2. ↑ Goodman, H. Maurice: ”Thyroid gland”, Basic Medical Endocrinology, s. 49. (Fourth edition) Academic Press, 2009. ISBN 978-0-12-373975-9 (englanniksi)
  3. ↑ a b Ross, Michael H. ja Pawlina, Wojciech: Histology. A Text and Atlas, s. 704. (Fifth Edition) Lippincott Williams & Wilkins, 2006. ISBN 978-0-7817-7221-1 (englanniksi)
  4. ↑ Struumat Suomen kipirauhaspotilaat ry. Viitattu 7.8.2024.
  5. ↑ Väitöstiedote, Helsinki.fi (Arkistoitu – Internet Archive)

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