Zhou Pinxi played for the Guangzhou Evergrande youth team before being sent on loan to third tier club Inner Mongolia Caoshangfei for the 2020 China League Two campaign.[1] On his return to Guangzhou he made his debut for the club on 3 July 2021 in a AFC Champions League game against Kitchee in a 1–0 defeat.[2] This was to be his only appearance for the club before being loaned out again, this time to third tier club Jiangxi Dark Horse Junior. After his loan period ended he made his move permanent on 18 April 2023.[3]
On 26 February 2024, Zhou signed for second tier club Heilongjiang Ice City.[4] He made his debut for the club in a league game on 9 March 2024 against his former club Guangzhou, in a 1–0 victory.[5] This was followed by his first goal for the team in a league game against Chongqing Tonglianglong in a 1–1 draw.[6]