Ysabel Ortega was born as Maria Ysabel Ortega Lapid in Laoag, Ilocos Norte to Lito Lapid[2][3][4] and Michelle Ortega, sister of actor Robert Ortega, making him Ysabel's uncle.[5]
Ortega also played a villainous and obsessed character again as the main antagonist Charlotte "Charlie" in Pusong Ligaw, and she became well known because of that role.
Later, she became one of the main cast of Araw Gabi as Nica Marcelo.[8] In 2019, she moved to GMA Network.
In 2020, she bagged the role of Jamie Robinson in the live-action adaptation of the hit anime series, Voltes V: Legacy. She did a lot of research and training before auditioning for the role.[9]