The museum features the history of the Army Medical Department from 1775 to the present, as well as medical contributions of the Army during times of peace and war. General areas covered are significant historical events, scientific and technological advances, development of the medical field service and contributions of key officers and enlisted personnel. Audio-visual presentations introduce the history of the Department. Two large galleries house the medical equipment, uniforms, medals, insignia and artwork that make up the museum's exhibits. Museum holdings include material on medical personnel, POWs in World War II's Pacific Theater, unit insignia and archival documents and photographs.
Outside the museum are examples of medical vehicles including ambulances and a fully equipped hospital trainambulance car. A Medical Combat Memorial honors the Army's combat medics.