In a subsequent reaction catalyzed by sulfoquinovosyl diacylglycerol synthase, the sulfoquinovose portion of UDP-sulfoquinovose is combined with diacyglycerol to produce the sulfolipidsulfoquinovosyl diacylglycerol (SQDG).[2]
This enzyme belongs to the family of hydrolases, specifically those acting on carbon-sulfur bonds. The systematic name of this enzyme class is UDP-6-sulfo-6-deoxyglucose sulfohydrolase. Other names in common use include sulfite:UDP-glucose sulfotransferase, and UDP-sulfoquinovose synthase. This enzyme participates in nucleotide sugars metabolism and glycerolipid metabolism.
The 3-dimensional structure of the enzyme is known from Protein Data Bank entries 1qrr (Mulichak et al., 1999), 1i24, 1i2b and 1i2c.
^Goddard-Borger, ED; Williams, SJ (20 February 2017). "Sulfoquinovose in the biosphere: occurrence, metabolism and functions". The Biochemical Journal. 474 (5): 827–849. doi:10.1042/BCJ20160508. PMID28219973.
Essigmann B, Hespenheide BM, Kuhn LA, Benning C (1999). "Prediction of the active-site structure and NAD(+) binding in SQD1, a protein essential for sulfolipid biosynthesis in Arabidopsis". Arch. Biochem. Biophys. 369 (1): 30–41. doi:10.1006/abbi.1999.1344. PMID10462438.
