Clancy Sigal, writing in The New York Times, described the novel as a study of faith under pressure: "Almost in thriller form, it is also a wise and illuminating meditation on the labyrinthine forces at work in a Roman Catholic Communist country like Poland (where Mr. Moore served with a United Nations relief group after the war)."[2]
According to critic Jo O'Donoghue, The Colour of Blood deals with the problem of how the modern Catholic Church "is to live in tandem with the secular authority".[3]
In her biography of Moore, Patricia Craig describes The Colour of Blood as a protest against intolerance, "with fanatical Catholicism presented as a destructive force. At the same time the Cardinal himself stands for another kind of Catholicism: moderate and incorruptible, and not unaccommodating of theological uncertainties".[4]