Talk:Leucine zipper

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Wiki Education Foundation-supported course assignment

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 27 August 2019 and 6 December 2019. Further details are available on the course page. Student editor(s): Ry19a.

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Leucine zipper binding to DNA???

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Why is the diagram being used showing a leucine zipper motif binding to DNA? Leucine zipper motifs are known protein:protein interaction domains, not DNA binding domains. The article itself even says so. EganioTalk 04:57, 4 February 2008 (UTC)[reply]__DTELLIPSISBUTTON__{"threadItem":{"timestamp":"2008-02-04T04:57:00.000Z","author":"Eganio","type":"comment","level":1,"id":"c-Eganio-2008-02-04T04:57:00.000Z-Leucine_zipper_binding_to_DNA???","replies":["c-ZayZayEM-2008-02-04T12:45:00.000Z-Eganio-2008-02-04T04:57:00.000Z"]}}-->


You sure? I'm pretty sure the Glick dictionary I used for "leucine scissors" said it was DNA-binding motif too. Additionally the article does say:

These proteins [-Leucine zipper regulatory proteins-] interact with the DNA as dimers (homo- or hetero-) and are also called basic zipper proteins (bZips).

which to me says leucine zipper molecules interact with DNA. You'll note the picture doesn't have the leucine-containing zipper domain interacting with the DNA. Rather the post-zipper "arms" or "jaws" of teh scissors do.--ZayZayEM (talk) 12:45, 4 February 2008 (UTC)[reply]__DTELLIPSISBUTTON__{"threadItem":{"timestamp":"2008-02-04T12:45:00.000Z","author":"ZayZayEM","type":"comment","level":2,"id":"c-ZayZayEM-2008-02-04T12:45:00.000Z-Eganio-2008-02-04T04:57:00.000Z","replies":["c-Eganio-2008-02-05T04:54:00.000Z-ZayZayEM-2008-02-04T12:45:00.000Z"]}}-->
OK, now I see what the diagram is representing...I was looking at it incorrectly. Sorry about that. EganioTalk 04:54, 5 February 2008 (UTC)[reply]__DTELLIPSISBUTTON__{"threadItem":{"timestamp":"2008-02-05T04:54:00.000Z","author":"Eganio","type":"comment","level":3,"id":"c-Eganio-2008-02-05T04:54:00.000Z-ZayZayEM-2008-02-04T12:45:00.000Z","replies":[]}}-->

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