"Sick of You" is, lyrically, a simple song, dealing with feelings of utter distaste for a despised one in a somewhat comical fashion:
Your face is gross You eat white toast You don't know what to do And just your luck You really suck And so I'm sick of you
Despite the somewhat simple song structure, the song is a fan favorite. Dave Brockie stated it to be his favorite Gwar song (usually because it means the concert is over) and it is the song played most often during the band's live shows.