Serine—tRNA ligase

Serine—tRNA ligase
Identifiers
EC no.6.1.1.11
CAS no.9023-48-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a serine—tRNA ligase (EC 6.1.1.11) is an enzyme that catalyzes the chemical reaction

ATP + L-serine + tRNASer AMP + diphosphate + L-seryl-tRNASer

The 3 substrates of this enzyme are ATP, L-serine, and tRNA(Ser), whereas its 3 products are AMP, diphosphate, and L-seryl-tRNA(Ser).

This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-serine:tRNASer ligase (AMP-forming). Other names in common use include seryl-tRNA synthetase, SerRS, seryl-transfer ribonucleate synthetase, seryl-transfer RNA synthetase, seryl-transfer ribonucleic acid synthetase, and serine translase. This enzyme participates in glycine, serine and threonine metabolism and aminoacyl-trna biosynthesis.

Structural studies

As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes 1SER, 1SES, 1SET, 1SRY, 1WLE, 2CIM, 2CJ9, 2CJA, 2CJB, 2DQ0, 2DQ1, 2DQ2, and 2DQ3.

References

  • Katze JR, Konigsberg W (1970). "Purification and properties of seryl transfer ribonucleic acid synthetase from Escherichia coli". J. Biol. Chem. 245 (5): 923–30. doi:10.1016/S0021-9258(18)63270-3. PMID 4906848.
  • Makman MH; Cantoni GL (1965). "Isolation of seryl and phenylalanyl ribonucleic acid synthetases from baker's yeast". Biochemistry. 4 (7): 1434–1442. doi:10.1021/bi00883a031.
  • Webster LT; Davie EW (1961). "Purification and properties of serine-activating enzyme from beef pancreas". J. Biol. Chem. 236 (2): 479–484. doi:10.1016/S0021-9258(18)64387-X. PMID 13783661.
  • Ohama T, Yang DC, Hatfield DL (1994). "Selenocysteine tRNA and serine tRNA are aminoacylated by the same synthetase, but may manifest different identities with respect to the long extra arm". Arch. Biochem. Biophys. 315 (2): 293–301. doi:10.1006/abbi.1994.1503. PMID 7986071.


Read other articles:

This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: The Motive film – news · newspapers · books · scholar · JSTOR (December 2017) (Learn how and when to remove this template message) 2017 filmThe MotiveSpanish release posterSpanishEl autor Directed byManuel Martín CuencaWritten byManuel Martín CuencaAleja...

 

Set of tax benefits for the Autonomous Region of MadeiraDecree-Law n. 500/80Government of Portugal Long title Authorizes the creation of a free zone in the Autonomous Region of Madeira Citation1980, c. 3493Territorial extentAutonomous Region of MadeiraEnacted13 Augusto 1980Assented to11 October 1980Signed byAntónio Ramalho EanesCommenced21 October 1980Administered byEuropean CommissionMinistry of FinanceRegional Government of MadeiraPortuguese Tax and Customs AuthoritySDM - So...

 

Cheval androcéphale ailé (à droite) sur un statère en or des Cénomans. Le cheval androcéphale est un motif de cheval à tête humaine et attributs masculins, présent sur de nombreuses pièces de monnaie celtiques de l'Antiquité frappées par des peuples celtes établis sur la façade atlantique, surtout en Armorique. Ce motif est présent sur les monnaies des Vénètes, des Aulerques Cénomans et des Trévires. Il orne également un couvercle de cruche retrouvé à Reinheim dans l'oue...

Artikel ini perlu diwikifikasi agar memenuhi standar kualitas Wikipedia. Anda dapat memberikan bantuan berupa penambahan pranala dalam, atau dengan merapikan tata letak dari artikel ini. Untuk keterangan lebih lanjut, klik [tampil] di bagian kanan. Mengganti markah HTML dengan markah wiki bila dimungkinkan. Tambahkan pranala wiki. Bila dirasa perlu, buatlah pautan ke artikel wiki lainnya dengan cara menambahkan [[ dan ]] pada kata yang bersangkutan (lihat WP:LINK untuk keterangan lebih lanjut...

 

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada Desember 2022. Sejarah Kekaisaran Jerman Nama SophieAsal nama Sophie, Grand Duchess of Saxe-Weimar-EisenachPasang lunas Januari 1880Diluncurkan 10 November 1881Mulai berlayar 10 Agustus 1882Dipensiunkan 7 April 1899Nasib Dibongkar, 1921 Ciri-ciri umum Kelas dan jeni...

 

Family of European lawn games Not to be confused with the later game of trucco or lawn billiards. Ground billiardsGround billiards in 15th-century France (1480 woodcut, based on the Saint-Lô Tapestry). This version uses a port (arch) and conical king pin, is bounded by a wicker railing, and appears to make use of one ball per player, with more than two players.First played14th–15th century EuropeCharacteristicsContactNoTeam membersSingle opponents shown in illustrations; doubles or teams ...

Italian criminologist (1856–1929) Enrico FerriBorn(1856-02-25)25 February 1856San Benedetto Po, Lombardy–VenetiaDied12 April 1929(1929-04-12) (aged 73)Rome, Kingdom of ItalyScientific careerAcademic advisorsCesare Lombroso Criminology and penology Theory Anomie Biosocial criminology Broken windows Collective efficacy Crime analysis Criminalization Differential association Deviance Expressive function of law Labeling theory Psychopathy Rational choice Risk & actuarial criminology ...

 

2016年美國總統選舉 ← 2012 2016年11月8日 2020 → 538個選舉人團席位獲勝需270票民意調查投票率55.7%[1][2] ▲ 0.8 %   获提名人 唐納·川普 希拉莉·克林頓 政党 共和黨 民主党 家鄉州 紐約州 紐約州 竞选搭档 迈克·彭斯 蒂姆·凱恩 选举人票 304[3][4][註 1] 227[5] 胜出州/省 30 + 緬-2 20 + DC 民選得票 62,984,828[6] 65,853,514[6]...

 

土库曼斯坦总统土库曼斯坦国徽土库曼斯坦总统旗現任谢尔达尔·别尔德穆哈梅多夫自2022年3月19日官邸阿什哈巴德总统府(Oguzkhan Presidential Palace)機關所在地阿什哈巴德任命者直接选举任期7年,可连选连任首任萨帕尔穆拉特·尼亚佐夫设立1991年10月27日 土库曼斯坦土库曼斯坦政府与政治 国家政府 土库曼斯坦宪法 国旗 国徽 国歌 立法機關(英语:National Council of Turkmenistan) ...

يفتقر محتوى هذه المقالة إلى الاستشهاد بمصادر. فضلاً، ساهم في تطوير هذه المقالة من خلال إضافة مصادر موثوق بها. أي معلومات غير موثقة يمكن التشكيك بها وإزالتها. (ديسمبر 2018) بطولة أفريقيا تحت 17 سنة لكرة القدم 1995تفاصيل المسابقةالبلد المضيفماليالفرق8 (من 1 اتحاد كونفدرالي)المر�...

 

Ontario based conservation authority This article relies excessively on references to primary sources. Please improve this article by adding secondary or tertiary sources. Find sources: Credit Valley Conservation – news · newspapers · books · scholar · JSTOR (August 2011) (Learn how and when to remove this message) Credit Valley ConservationFoundedMay 13, 1954TypeConservation authorityFocusHabitat conservation, water conservation, wildlife managementLo...

 

Полинезийский треугольник Полинези́йский треуго́льник — условный географический район в Тихом океане. Полинезийский треугольник не имеет четких границ, и принято считать, что он находится внутри воображаемых линий, соединяющих Гавайские острова и Новую Зеландию (�...

British mandate from 1916 to 1961 Cameroons redirects here. For other uses, see Cameroon (disambiguation). British Cameroon1916–1961 Flag Coat of arms Anthem: God Save the King (1916–1952)God Save the Queen (1952–1961)StatusMandate of the United KingdomCapitalBueaCommon languagesEnglish (official)Duala, Oroko, Grassfields, Fula, Kanuri widely spokenReligion Christianity (southern area)Islam (northern area)Historical eraWorld War I• Kamerun partitioned 20 July 1916�...

 

MANLogo Stato Germania Forma societariaSocietà europea Borse valoriBorsa di Francoforte: MAN ISINDE0005937007 e DE0005937031 Fondazione1758 Chiusura2021 (confluita in Traton) Sede principaleMonaco GruppoVolkswagen Aktiengesellschaft Persone chiaveGeorg Pachta-Reyhofen (AD), Ferdinand Piech (Presidente del Consiglio di Sorveglianza) SettoreMetalmeccanica Prodotti Autocarri Autobus Motori Fatturato12 miliardi € (2009) Utile netto270 milioni € (2009) Dipendenti47.740 (2009) Sito webwww...

 

كارليس بيريز (بالإسبانية: Carles Pérez)‏  بيريز مع برشلونة عام 2019. معلومات شخصية الاسم الكامل كارليس بيريز سايول[1] الميلاد 16 فبراير 1998 (العمر 26 سنة)جرانوليريس، إسبانيا الطول 1.73 م (5 قدم 8 بوصة)[2][2] مركز اللعب وسط الجنسية إسباني معلومات النادي النادي الحالي س...

1967 single by Small Faces Itchycoo ParkDutch picture sleeveSingle by Small FacesB-sideI'm Only DreamingReleased4 August 1967Recorded3–7 July 1967[1]StudioOlympic (London)GenrePsychedelic rock[2]psychedelic pop[3]music hall[4]Length2:45LabelImmediateSongwriter(s) Steve Marriott Ronnie Lane Producer(s) Steve Marriott Ronnie Lane Small Faces singles chronology Here Come the Nice (1967) Itchycoo Park (1967) Tin Soldier (1967) Audio samplefilehelp Itchycoo Park i...

 

2002 studio album by B2KSanta Hooked Me UpStudio album by B2KReleasedOctober 29, 2002Genre R&B pop Christmas LabelEpicB2K chronology B2K: The Remixes - Volume 1(2002) Santa Hooked Me Up(2002) Pandemonium!(2002) Professional ratingsReview scoresSourceRatingAllmusic [1]Entertainment WeeklyF [2]Rolling Stone(unfavorable) [3] Santa Hooked Me Up is the second studio album and only Christmas album by R&B group B2K, released on October 29, 2002. It was release...

 

Frédéric Mistral Frédéric MistralPseudonymMèste Franc[1], Gui de Mount-Pavoun[1], Cousinié Macàri[1], Michèu Gai[1], Lou Cascarelet[1], Grand la Borgno[1], Lou Felibre de Bello Visto[1], Un Maianen[1], Lou Felibre dóu Mas[1], Antoine Chansroux[1], Lou Canounge de N-D. de Casten[1], Lou Felibre de Bèuvezet[1], Lou Felibre Calu[1], Jan Chaplo Verne[1], Un Jouine Felibre[1], Lou Medecin di Torro[1], Tounin Clapo[1], Lou Tout-Obro[1] och Ambròsi Boufarel[2]Född8 september 1830 Maillan...

French painter (1803–1860) Frédéric Bourgeois de Mercey, by Jean-Baptiste Louis Gros (c. 1856) View of the Old Port of Bastia Frédéric Bourgeois de Mercey (20 May 1803, Paris – 6 September 1860, La Faloise) was a French painter, art critic, travel writer, and novelist. Biography His father was Louis-Frédéric Bourgeois de Mercey [fr], a property manager, originally from Lorraine. He was interested in landscape art; travelling throughout northwestern Europe from 1828 and ...

 

UNESCO World Heritage Site in Greece Tunnel of EupalinosInside one of the most spacious parts of the Eupalinian aqueductOverviewLocationSamos Island, GreeceCoordinates37°41′38″N 26°55′48″E / 37.694°N 26.930°E / 37.694; 26.930StatusOpenOperationOpenedcirca 6th century BCETechnicalDesign engineerEupalinosLength1036 m UNESCO World Heritage SitePart ofPythagoreion and Heraion of SamosCriteriaCultural: (ii)(iii)Reference595-001Inscription1992 (16th Session)...