Rotavirus cis-acting replication element

Rotavirus cis-acting replication element (CRE)
Predicted secondary structure and sequence conservation of Rota_CRE
Identifiers
SymbolRota_CRE
RfamRF00501
Other data
RNA typeCis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

This family represents a rotavirus cis-acting replication element (CRE) found at the 3'-end of rotavirus mRNAs. The family is thought to promote the synthesis of minus strand RNA to form viral dsRNA.[1]

References

  1. ^ Chen D, Barros M, Spencer E, Patton JT (April 2001). "Features of the 3'-consensus sequence of rotavirus mRNAs critical to minus strand synthesis". Virology. 282 (2): 221–229. doi:10.1006/viro.2001.0825. PMID 11289804.
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