Ramandeep Singh is an Indian molecular biologist , geneticist and a professor at the Translational Health Science and Technology Institute . Known for his studies on the pathogenesis of Mycobacterium tuberculosis , he is a former research fellow of the National Institutes of Health . The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development , one of the highest Indian science awards, for his contributions to biosciences, in 2014.[ 1]
Biography
University of Delhi
Ramandeep Singh, born in New Delhi, graduated in science from the South Campus of the University of Delhi and continued his education there to earn a master's degree and later, a PhD in 2003.[ 2] He did his post doctoral work on research fellowship from the National Institutes of Health at the National Institute of Allergy and Infectious Diseases . Subsequently, he joined the Translational Health Science and Technology Institute as a scientist where he serves as an associate professor at the Vaccine and Infectious Disease Research Center (VIDRC)[ 3] and hosts a number of scientists at his laboratory.[ 4]
Professional profile
Singh's research focus is on understanding the metabolic pathways that enable Mycobacterium tuberculosis to survive in stressful conditions [ 2] and he is known to have characterized genes associated with its pathogenesis such as tyrosine phosphatases .[ 5] He has undertaken vaccine development projects as the principal investigator.[ 6] His studies have been documented by way of a number of articles[ note 1] and ResearchGate , an online repository of scientific articles has listed 38 of them.[ 7] He is also a member of the Biosafety Committee of the Regional Centre for Biotechnology , an autonomous organization funded by the Department of Biotechnology and the United Nations Educational, Scientific and Cultural Organization (UNESCO), as an external expert.[ 8]
Awards and honors
The Department of Biotechnology (DBT) of the Government of India awarded him the National Bioscience Award for Career Development , one of the highest Indian science awards in 2014.[ 1]
Selected bibliography
Negi, Beena; Poonan, Prija; Ansari, Mohammad Fawad; Kumar, Deepak; Aggarwal, Sakshi; Singh, Ramandeep; Azam, Amir; Rawat, Diwan S. (2018). "Synthesis, antiamoebic activity and docking studies of metronidazole-triazole-styryl hybrids". European Journal of Medicinal Chemistry . 150 : 633–641. doi :10.1016/j.ejmech.2018.03.033 . PMID 29558734 .
Agarwal, Sakshi; Tiwari, Prabhakar; Deep, Amar; Kidwai, Saqib; Gupta, Shamba; Thakur, Krishan Gopal; Singh, Ramandeep (24 February 2018). "System-Wide Analysis Unravels the Differential Regulation and In Vivo Essentiality of Virulence-Associated Proteins B and C Toxin-Antitoxin Systems of Mycobacterium tuberculosis". The Journal of Infectious Diseases . 217 (11): 1809–1820. doi :10.1093/infdis/jiy109 . PMID 29529224 . S2CID 3865758 .
Deep, Amar; Kaundal, Soni; Agarwal, Sakshi; Singh, Ramandeep; Thakur, Krishan Gopal (29 October 2017). "Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin-antitoxin assembly" . The FEBS Journal . 284 (23): 4066–4082. doi :10.1111/febs.14289 . PMID 28986943 .
Notes
^ Please see Selected bibliography section
References
External links
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