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Putrescine aminotransferase (EC 2.6.1.82, putrescine-alpha-ketoglutarate transaminase, YgjG, putrescine:alpha-ketoglutarate aminotransferase, PAT, putrescine:2-oxoglutarate aminotransferase, putrescine transaminase) is an enzyme with systematic name butane-1,4-diamine:2-oxoglutarate aminotransferase.^[1][2][3] This enzyme catalyses the following chemical reaction

putrescine + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ 1-pyrroline + L-glutamate + H₂O (overall reaction)

(1a) putrescine + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ 4-aminobutanal + L-glutamate

(1b) 4-aminobutanal ${\displaystyle \rightleftharpoons }$ 1-pyrroline + H₂O (spontaneous)

This enzyme is a pyridoxal-phosphate protein.

• Putrescine+aminotransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)