Proliferating trichilemmal cyst

Proliferating trichilemmal cyst
Other namesPilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor
Proliferating tricholemmal (pilar) cyst
SpecialtyDermatology

Proliferating trichilemmal cysts (also known as a pilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor)[1] is a cutaneous condition, characterized by proliferations of squamous cells forming scroll-like structures.[1][2]: 678 

Signs and symptoms

The tumors, which are typically found in regions like the scalp with a high density of hair follicles, can be solid or solid cystic. Proliferating trichilemmal cyst frequently manifests clinically as a subcutaneous nodule that gradually grows into a big nodular mass. Rapid growth in some cases may be a sign of malignant development into cancer.[3]

Diagnosis

Histologically, Proliferating trichilemmal cysts are distinguished by trichilemmal keratinization, which is the sudden change from nucleated epithelium to anucleated keratinized cells without a granular layer.[4] The differential diagnosis include trichilemmal cyst and Turban tumor.[5]

Treatment

Surgical excision is the treatment of choice for proliferating trichilemmal cysts.[4]

Epidemiology

Proliferating trichilemmal cysts make up 0.1% of all skin tumors.[4] Most patients with these tumors are older women, and 90% of patients with these lesions appear on the scalp.[6]

See also

References

  1. ^ a b Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  3. ^ Valerio, Ediel; Parro, Fernando Henrique Sgarbi; Macedo, Mariana Petaccia de; Pinto, Clovis Antonio Lopes (2019). "Proliferating trichilemmal cyst with clinical, radiological, macroscopic, and microscopic correlation". Anais Brasileiros de Dermatologia. 94 (4). FapUNIFESP (SciELO): 452–454. doi:10.1590/abd1806-4841.20198199. ISSN 1806-4841. PMC 7007035. PMID 31644620.
  4. ^ a b c Capurso-García, Marino Antonio; Bautista-Piña, Verónica; Pomerantz, Alan; Galnares-Olalde, Javier Andrés; Blachman-Braun, Ruben; Rodríguez-Rodríguez, Sergio; Goldberg-Murow, Monica (2016). "Atypical Proliferating Trichilemmal Cyst with Malignant Breast Skin Transformation: A Case Report and Review of the Literature". Case Reports in Oncological Medicine. 2016. Hindawi Limited: 1–4. doi:10.1155/2016/7481569. ISSN 2090-6706. PMC 4923530. PMID 27403361.
  5. ^ Chang, S.J.; Sims, J.; Murtagh, F.R.; McCaffrey, J.C.; Messina, J.L. (2006-03-01). "Proliferating Trichilemmal Cysts of the Scalp on CT". American Journal of Neuroradiology. 27 (3): 712–714. ISSN 0195-6108. PMC 7976987. PMID 16552022. Retrieved 2024-05-11.
  6. ^ Deshmukh, BhaktiD; Kulkarni, MedhaP; Momin, YasminA; Sulhyan, KalpanaR (2014). "Malignant proliferating trichilemmal tumor: A case report and review of literature". Journal of Cancer Research and Therapeutics. 10 (3): 767. doi:10.4103/0973-1482.136036. ISSN 0973-1482. PMID 25313781.

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