Phytochemical investigation of the soil microfungus Eupenicillum parvum led to the isolation of two new compounds: a chromone derivative euparvione and a new mycophenolic derivative euparvilactone, as well as thirteen known compounds. Several isolated compounds were evaluated for in vitrobinding assays using opioid receptors (subtypes δ, κ, and μ) and cannabinoid receptors (CB1 and CB2). Compound 10 displayed the best selective μ-opioid receptor and CB1 receptor binding affinities showing values of 47% and 52% at a 10 μM concentration, respectively. These findings provide insight into the potential therapeutic utility of this class of compounds.[8]
^Hakkō Kenkyūjo (2000). List of cultures: microorganisms. The Institute. ISBN4891140100.
^Rajeev K. Upadhyay; K.G. Mukerji; B. P. Chamola (2001). Biocontrol Potential and its Exploitation in Sustainable Agriculture: Volume 1: Crop Diseases, Weeds, and Nematodes. Springer Science & Business Media. ISBN0306464608.
^B.H. Dunford; D. Dolphin; K.N. Raymond; L. Sieker (2012). The Biological Chemistry of Iron: A Look at the Metabolism of Iron and Its Subsequent Uses in Living Organisms Proceedings of the NATO Advanced Study Institute held at Edmonton, Alberta, Canada, August 13 – September 4, 1981. Springer Science & Business Media. ISBN9400978820.
