Pancho is a male nickname for the given name Francisco (Spanish and Portuguese equivalent of Francis). The feminine form is Pancha. It is also sometimes used as a surname. Notable people with the name include:

• Pancho Barnes (1901–1975), early female American aviator
• Pancho Carter (born 1950), American retired race car driver
• Pancho Coimbre (1909–1989), Puerto Rican baseball player
• Pancho Córdova (1916–1990), Mexican character actor
• Pancho Daniel (died 1858), bandit in what is now California
• Pancho Fierro (c. 1807/1809–1879), Peruvian painter
• Pancho Gonzales (1928–1995), American tennis player
• Pancho Gonzales (footballer) (1926–2016), Argentine football player, and manager
• Pancho Guedes (1925–2015), Portuguese architect, sculptor, and painter
• Francisco Guilledo (1901–1925), Filipino world champion boxer
• Pancho Herrera (1934–2005), Major League Baseball player
• Franklin Huddle (born 1943), American diplomat
• Pancho Martin (1925–2012), trainer of thoroughbred racehorses
• Pancho Prin (1930–2003), Venezuelan musician, singer, and composer
• Ferenc Puskás (1927–2006), Hungarian footballer
• Francisco Ramírez (governor) (1786–1821), Argentine provincial governor
• José Francisco Ramírez (born 1976), Honduran footballer
• Pancho Segura (1921–2017), Ecuadorian-born American tennis player
• Francisco Varallo (1910–2010), Argentine footballer
• Pancho Villa (1878–1923), Mexican revolutionary
• Pancho Vladigerov (1899–1978), Bulgarian composer, pianist, and pedagogue

• Michael Locke (stuntman) (born 1979), a stuntman on the Welsh television programme Dirty Sanchez

• Pancho, sidekick of The Cisco Kid
• Pancho, in the Spanish language children's television series Plaza Sésamo
• Pancho, character in the Townes Van Zandt song Pancho and Lefty

• Cassa Pancho, founder of British ballet company Ballet Black
• Pedro Pancho (born 1934), Filipino politician

• Paco
• Panchito, diminutive of Pancho
• Pancha (disambiguation), female given name
• All pages with titles beginning with Pancho
• All pages with titles containing Pancho