N'-Formylkynurenine

N′-Formylkynurenine
Names
Systematic IUPAC name
(2S)-2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid
Other names
N′-Formyl-L-kynurenine
Identifiers
3D model (JSmol)
ChEBI
MeSH N'-formylkynurenine
UNII
  • C1=CC=C(C(=C1)C(=O)C[C@@H](C(=O)O)N)NC=O
Properties
C11H12N2O4
Molar mass 236.227 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N′-Formylkynurenine is an intermediate in the catabolism of tryptophan. It is a formylated derivative of kynurenine. The formation of N′-formylkynurenine is catalyzed by heme dioxygenases.[1]

See also

References

  1. ^ Basran, Jaswir; Efimov, Igor; Chauhan, Nishma; Thackray, Sarah J; Krupa, James L; Eaton, Graham; Griffith, Gerry A; Mowat, Christopher G; Handa, Sandeep; Raven, Emma Lloyd (2011). "The Mechanism of Formation of N-Formylkynurenine by Heme Dioxygenases". Journal of the American Chemical Society. 133 (40): 16251–16257. doi:10.1021/ja207066z. PMC 3210546. PMID 21892828.
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