Myosin-heavy chain myopathy

Myosin-heavy chain myopathy (MYHM) is a genetic muscle disease found primarily in the American Quarter Horse and crossbred horses with significant Quarter Horse bloodlines.

It was added to the AQHA genetic testing panel in 2022.[1] It is a genetic dominant condition, though not all horses who inherit the gene will show clinical signs of being affected and the environmental triggers are not well understood at present. An estimated 7% of all Quarter Horses carry this gene. There are two forms, both linked to the same genetic variant. Affected horses may exhibit one or both forms. The first is Immune-Mediated Myositis (IMM). It may occur in response to a vaccine or infectious agent, where the immune system misinterprets the muscle cells as foreign and rapidly attacks them. Horses initially experience stiffness, weakness, and a decreased appetite followed by the rapid loss of 40% of muscle mass within 72 hours. The second presentation of MYHM is Nonexertional Rhabdomyolysis (compare to PSSM, below) and often presents as stiffness and possible swelling of muscles along the back and haunches without exercise. Clinical signs include pain, muscle cramping, and muscle damage, but may or may not result in muscle loss. When triggered, horses can recover but may have more frequent episodes. Horses that are homozygous (My/My) may have more severe symptoms.[2]

References

  1. ^ "AQHA Adds MYHM Testing to Genetic Health Panel". American Quarter Horse Association. Retrieved 7 March 2024.
  2. ^ "Myosin-Heavy Chain Myopathy (MYHM)". American Quarter Horse Association. Retrieved 7 March 2024.

Read other articles:

Je partirai

Je partiraiSingel oleh Anggundari album EchosDirilisMei 2011FormatDigital download; CD SingleDirekam2010GenrePopDurasi4:22LabelApril Earth, WarnerPenciptaAnggun, Marie Bastide, Christophe Cottin, Gioacchino MauriciProduserAnggun Je partirai adalah singel pertama oleh penyanyi Indonesia Anggun C. Sasmi dari album internasional kelimanya untuk versi berbahasa Prancis yang bertajuk Echoes. Lagu ini juga direkam dalam bahasa Indonesia dengan judul Yang Terlarang dalam album versi berbahasa Inggri...

 

Kegubernuran Al Muthanna

Kegubernuran Al Muthanna Ibu kota Samawah Kota terbesar Kepala pemerintah Luas (km²) 83.268 Populasi (jiwa) 1.035.000 Kepadatan (/km²) 6 Bahasa Arab Komposisi etnis Kegubernuran Al Muthanna (Arab: المثنى) merupakan sebuah kegubernuran di Irak. Kegubernuran ini terletak di bagian selatan di negara itu. Dekat perbatasan Arab Saudi. Kegubernuran ini memiliki luas wilayah 83.268 km² dengan memiliki jumlah penduduk 1.035.000jiwa (2015). Ibu kotanya ialah Samawah. Pada tahun 1976 mer...

 

North Dakota

U.S. state This article is about the U.S. state. For other uses, see North Dakota (disambiguation). State in the United StatesNorth Dakota Dakȟóta waziyata (Lakota)StateState of North Dakota FlagSealNickname(s): Peace Garden State,Roughrider State, Flickertail State, Heaven on EarthMotto(s): Liberty and Union, Now and Forever, One and InseparableAnthem: North Dakota HymnMap of the United States with North Dakota highlightedCountryUnited StatesBefore statehoodDakota TerritoryA...

Integral Riemann

Integral sebagai luas daerah pada bagian bawah kurva. Urutan jumlah Riemann pada partisi reguler dari suatu interval. Bilangan diatas adalah total luas persegi panjang, yang konvergensinya ke integral fungsi. Partisi tidak harus reguler, seperti yang ditunjukkan dibagian ini. Aproksimasi bekerja selama lebar setiap sub-pembagian cenderung ke nol. Kalkulus Teorema dasar Limit fungsi Kontinuitas Teorema nilai purata Teorema Rolle Diferensial Definisi Turunan (perumuman) Tabel turunan Difer...

 

Jorlang Hataran, Simalungun

Jorlang HataranKecamatanKantor Kecamatan Jorlang HataranPeta lokasi Kecamatan Jorlang HataranNegara IndonesiaProvinsiSumatera UtaraKabupatenSimalungunPemerintahan • Camat-Populasi • Total- jiwaKode Kemendagri12.08.06 Kode BPS1209080 Luas- km²Desa/kelurahan12/1 Jorlang Hataran adalah sebuah kecamatan di Kabupaten Simalungun, Sumatera Utara, Indonesia. Pemerintahan Kecamatan Dolok Panribuan terdiri dari 1 kelurahan dan 12 nagori: Kelurahan Tiga Balata Nagori Bah Bi...

 

Rempah-rempah

Beberapa rempah-rempah asal Indonesia sebagai obat atau bumbu masakan. Rempah-rempah adalah bagian tumbuhan yang beraroma atau berasa kuat yang digunakan dalam jumlah kecil di makanan sebagai pengawet atau perisa dalam masakan. Rempah-rempah biasanya dibedakan dengan tanaman lain yang digunakan untuk tujuan yang mirip, seperti tanaman obat, sayuran beraroma, dan buah kering. Rempah-rempah merupakan barang dagangan paling berharga pada zaman prakolonial. Banyak rempah-rempah dulunya digunakan ...

Papa Onorio II

Disambiguazione – Se stai cercando l'antipapa dell'XI secolo, vedi Antipapa Onorio II. Papa Onorio II163º papa della Chiesa cattolicaElezione15 dicembre 1124 Insediamento21 dicembre 1124 Fine pontificato13 febbraio 1130(5 anni e 60 giorni) Cardinali creativedi Concistori di papa Onorio II Predecessorepapa Callisto II Successorepapa Innocenzo II  NomeLamberto detto Scannabecchi NascitaFiagnano, 9 febbraio 1060 Consacrazione a vescovo1117 Creazione a cardinale1099 da papa Urb...

 

Menardo Guevarra

Solicitor General of the Philippines In this Philippine name, the middle name or maternal family name is Ilasco and the surname or paternal family name is Guevarra. The HonorableMenardo GuevarraGuevarra official portrait as Justice Secretary in 2019Solicitor General of the PhilippinesIncumbentAssumed office June 30, 2022PresidentBongbong MarcosPreceded byJose Calida59th Secretary of JusticeIn officeApril 5, 2018 – June 30, 2022PresidentRodrigo DutertePreceded byVitalia...

 

Nia Griffith

British Labour politician The subject of this article is standing for re-election to the House of Commons of the United Kingdom on 4 July, and has not been an incumbent MP since Parliament was dissolved on 30 May. Some parts of this article may be out of date during this period. Please feel free to improve this article (but note that updates without valid and reliable references will be removed) or discuss changes on the talk page. Dame Nia GriffithDBE MPOfficial portrait, 2020M...

Damon Wayans Jr.

American actor and comedian (born 1982) For the actor's father, see Damon Wayans. Damon Wayans Jr.Wayans in 2022BornDamon Kyle Wayans Jr. (1982-11-18) November 18, 1982 (age 41)[1]Huntington, Vermont, U.S.Occupations Actor comedian Years active1994–presentSpouse Samara Saraiva ​(m. 2016)​Children2ParentDamon Wayans (father)RelativesWayans family Damon Kyle Wayans Jr. (born November 18, 1982) is an American actor and comedian. He starred as Brad...

 

Open BO

Open BOGenre Drama Komedi PembuatMonty TiwaDitulis oleh Kurnia Cahya Putra Azzam Fi Rullah SutradaraReka WijayaPemeran Wulan Guritno Winky Wiryawan Elmayana Sabrenia Ariyo Wahab Cathy Fakandi Negara asalIndonesiaBahasa asliBahasa IndonesiaJmlh. musim1Jmlh. episode8ProduksiProduser eksekutif Monika Rudijono Indra Yudhistira Produser Wendhy Sepriwantono Omar Aly Adly SinematografiRollie MarkianoPengaturan kameraMulti-kameraDurasi37—40 menitRumah produksiAmadeus SinemagnaRilis asliJaringanVid...

 

Butte County, California

County in California, United States County in California, United StatesButte County, CaliforniaCountyCounty of ButteButte County in 2005, with a view of the Sutter Buttes in the background SealWordmarkNickname(s): The Land of Natural Wealth and BeautyInteractive map of Butte CountyLocation in the state of CaliforniaCountryUnited StatesStateCaliforniaIncorporatedFebruary 18, 1850[1]Named forThe nearby Sutter ButtesCounty seatOrovilleLargest cityChicoGovernment • TypeCo...

Killing of Zijie Yan

In this Chinese name, the family name is Yan. 2023 homicide in Chapel Hill, North Carolina Killing of Zijie YanDr. Zijie YanLocationCaudill Labs, University of North Carolina, Chapel Hill, North Carolina, U.S.DateAugust 28, 2023; 9 months ago (2023-08-28) c. 1:02 p.m. (EDT)Attack typeSchool shooting, murderWeapon9 mm handgun[1]VictimZijie YanAccusedTailei QiChargesFirst-degree murder On August 28, 2023, Zijie Yan, an associate professor at the University of Nort...

 

Transgender personnel in the United States military

Transgender personnel in the United States militaryProtesters outside the U.S. Army Recruiting Center on July 26, 2017, respond to President Donald Trump's tweets that transgender people would no longer be allowed to serve in the U.S. military.Albert Cashier, a Union Army soldier in the Civil War who was born Jennie Irene HodgersLegal StatusCurrent statusNo restrictionsCurrent lawExecutive Order on Enabling All Qualified Americans to Serve Their Country in UniformPrevious laws Executive Orde...

 

National Register of Historic Places listings in New York

Map of the counties of New York State Map of the counties of New York State Buildings, sites, districts, and objects in New York listed on the National Register of Historic Places: There are over 6,000 properties and districts listed on the National Register of Historic Places in New York State. Some are listed within each one of the 62 counties in New York State. Of these, 264 are further designated as National Historic Landmarks.           This National Park...

Cristian Zorzi

Italian cross-country skier Cristian ZorziZorzi in 2006Country ItalyBorn (1972-08-14) 14 August 1972 (age 51)Cavalese, ItalySki clubG.S. Fiamme Gialle[1]World Cup careerSeasons17 – (1994–2010)Starts186Podiums12Wins5Overall titles0 – (7th in 2002)Discipline titles0 Medal record Men's cross-country skiing Representing  Italy Olympic Games 2006 Turin 4 × 10 km relay 2002 Salt Lake City 4 × 10 km&...

 

1996 United States presidential election in Indiana

Main article: 1996 United States presidential election 1996 United States presidential election in Indiana ← 1992 November 5, 1996 2000 →   Nominee Bob Dole Bill Clinton Ross Perot Party Republican Democratic Reform Home state Kansas Arkansas Texas Running mate Jack Kemp Al Gore Pat Choate Electoral vote 12 0 0 Popular vote 1,006,693 887,424 224,299 Percentage 47.13% 41.55% 10.50% County Results Dole   40-50%   50-60%  &...

 

غررردس كراس (باكينجهامشير)

غررردس كراس   الإحداثيات 51°35′18″N 0°33′11″W / 51.5882°N 0.553°W / 51.5882; -0.553   [1] تقسيم إداري  البلد المملكة المتحدة[2][3]  التقسيم الأعلى باكينغهامشير  [لغات أخرى]‏  خصائص جغرافية  المساحة 10.88 كيلومتر مربع  عدد السكان  عدد السكان 8017 (201...

Yttrium (90Y) tacatuzumab tetraxetan

Monoclonal antibody Yttrium (90Y) tacatuzumab tetraxetanMonoclonal antibodyTypeWhole antibodySourceHumanized (from mouse)Targetα-fetoproteinClinical dataATC codenoneIdentifiersCAS Number476413-07-7 NChemSpidernoneUNIIGJ2416WK6YChemical and physical dataFormulaC6470H9971N1712O2007S4290YMolar mass145 kg/mol NY (what is this?)  (verify) Yttrium (90Y) tacatuzumab tetraxetan is an investigational humanized monoclonal antibody intended for the treatment of cancer.[...

 

FIS Alpine World Ski Championships 2021 – Women's downhill

Women's downhill at the FIS Alpine World Ski Championships 2021LocationCortina d'Ampezzo, ItalyDate13 FebruaryCompetitors31 from 16 nationsWinning time1:34.27Medalists  Corinne Suter    Switzerland Kira Weidle   Germany Lara Gut-Behrami    Switzerland← 20192023 → FIS Alpine World Ski Championships 2021CombinedmenwomenDownhillmenwomenGiant slalommenwomenSlalommenwomenSuper-GmenwomenParallel g...