Molybdenum cofactor guanylyltransferase

Molybdenum cofactor guanylyltransferase
Identifiers
EC no.2.7.7.77
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

Molybdenum cofactor guanylyltransferase (EC 2.7.7.77, MobA, MoCo guanylyltransferase) is an enzyme with systematic name GTP:molybdenum cofactor guanylyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction:

GTP + molybdenum cofactor diphosphate + guanylyl molybdenum cofactor

Catalyses the guanylation of the molybdenum cofactor.

References

  1. ^ Lake MW, Temple CA, Rajagopalan KV, Schindelin H (December 2000). "The crystal structure of the Escherichia coli MobA protein provides insight into molybdopterin guanine dinucleotide biosynthesis". The Journal of Biological Chemistry. 275 (51): 40211–7. doi:10.1074/jbc.m007406200. PMID 10978347.
  2. ^ Temple CA, Rajagopalan KV (December 2000). "Mechanism of assembly of the Bis(Molybdopterin guanine dinucleotide)molybdenum cofactor in Rhodobacter sphaeroides dimethyl sulfoxide reductase". The Journal of Biological Chemistry. 275 (51): 40202–10. doi:10.1074/jbc.m007407200. PMID 10978348.
  3. ^ Guse A, Stevenson CE, Kuper J, Buchanan G, Schwarz G, Giordano G, Magalon A, Mendel RR, Lawson DM, Palmer T (July 2003). "Biochemical and structural analysis of the molybdenum cofactor biosynthesis protein MobA". The Journal of Biological Chemistry. 278 (28): 25302–7. doi:10.1074/jbc.m302639200. PMID 12719427.

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