Following is a list of senators of Saône-et-Loire, people who have represented the department of Saône-et-Loire in the Senate of France.

Senators for Saône-et-Loire under the French Third Republic were:^[1]

Senators for Saône-et-Loire under the French Fourth Republic were:^[2]

• François Mercier (1946–1948)
• Julien Satonnet (1946–1948)
• Jean-Marie Thomas (1946–1948)
• Joseph Renaud (1948–1951)
• Henri Maupoil (1948–1958)
• Henri Varlot (1948–1958)
• Jules Pinsard (1951–1959)
• Marcel Legros (1958–1959)
• Xavier Perrier-Michon (1958–1959)

Senators for Saône-et-Loire under the French Fifth Republic:^[3][4]

• Roger Lagrange (1959–1967)
• Marcel Legros (1959–1971)
• Jules Pinsard (1959–1977)
• Marcel Mathy (1967–1982)
• Marcel Lucotte (1971–1995)
• France Lechenault (1977–1986)
• Bernard Desbrière (1982–1986)
• André Pourny (1986–2004)
• André Jarrot (1986–1995)
• René Beaumont (UMP) (2004–2014)
• Jean-Patrick Courtois (UMP) (2014–2015) Dismissed
• Jean-Paul Emorine (UMP) From 2014
• Jérôme Durain (Parti socialiste) From 2014
• Marie Mercier (Les Républicains), From June 2015, replacing Jean-Patrick Courtois, dismissed