This is a list of notable people who are from the Northwest Territories, Canada, or have spent a large part or formative part of their career in that territory.

• Leona Aglukkaq, former member of Parliament for the electoral district of Nunavut
• Roger Allen, former member of the Legislative Assembly of the Northwest Territories

• Zac Boyer, former National Hockey League right winger
• Tom Butters, former member of the Legislative Assembly of the Northwest Territories

• Mark Carney, governor of the Bank of England and former governor of the Bank of Canada

• Alex Debogorski, local truck driver and personality on Ice Road Truckers
• Paul Delorey, professional curler and former MLA and speaker in the Northwest Territories Legislature

• Jason Elliott, former professional ice hockey player
• Kingmeata Etidlooie, Inuk visual artist and sculptor

• Alice Masak French, Inuk author

• Brendan Green, Canadian team biathlete; participated in the 2010 Winter Olympics in the men's 4x7.5 km relay
• Jane Groenewegen, former member of the Legislative Assembly of the Northwest Territories from Hay River South
• Leela Gilday, Juno Award-winning Dene singer/songwriter from Yellowknife

• Sarah Hardisty, Dene elder and quillworker
• Courtney Howard, Physician and one0time leadership candidate, Green Party of Canada

• Helen Kalvak, Copper Inuit graphic artist
• Margot Kidder, film and television actress best known for playing Lois Lane in the Superman movies of the 1970s and 1980s
• Fred Koe, former member of the Legislative Assembly of the Northwest Territories
• Kevin Koe, world champion curler
• Shane Koyczan, poet and spoken word artist
• Floyd Kuptana, Inuk sculptor

• Joe McBryan (Buffalo Joe), president and owner of Buffalo Airways featured on Ice Pilots NWT
• Mikey McBryan, Buffalo Airways General Manager and featured on Ice Pilots NWT
• Rob McVicar, professional ice hockey goaltender
• Tobias Mehler, film and television actor best known for his roles on Battlestar Galactica and Stargate SG-1
• Vic Mercredi, Métis hockey player, first person born in the NWT to be drafted into the National Hockey League
• Dustin Milligan, film and television actor; lead actor in the first season of the Beverly Hills, 90210 spinoff

• Melaw Nakehk'o, Dene artist and film actress, known for role in The Revenant (2015)
• Phoebe Nahanni, Dene geographer
• Agnes Nanogak, Inuit artist
• Leslie Nielsen, actor, comedian, and producer best known for his roles on The Forbidden Planet and The Poseidon Adventure

• David Ruben Piqtoukun, Inuit artist and sculptor
• John Pollard, member of the Legislative Assembly of the Northwest Territories from 1987 until 1995

• Floyd Roland, Mayor of Inuvik; former Premier and member of the Legislative Assembly of the Northwest Territories

• Geoff Sanderson, former National Hockey League player
• Eric Schweig, Inuvialuit/Chippewa/Dene actor
• John Sissons, politician and the first judge of the Supreme Court of the Northwest Territories
• Donald Morton Stewart, former mayor and speaker of the Northwest Territories Legislature
• Les Stroud, filmmaker and survival expert; host of the television program Survivorman

• Ovilu Tunnillie, Inuit sculptor, member of the Royal Canadian Academy of Arts

• Greg Vaydik, National Hockey League player

• Max Ward, pioneering bush pilot and founder of Wardair airlines (later sold to Canadian Airlines)