• Tina Benko
• Julie Benz
• Lori Cardille
• Caitlin Clarke
• Dolores Costello
• Marpessa Dawn
• Lisa Emery
• Barbara Feldon
• Rita Gam
• Elizabeth Hartman
• Gillian Jacobs
• Cherie Johnson
• Kimmarie Johnson
• Shirley Jones
• Lorelei King
• Christine Laitta
• Heather Mazur
• Mitzi McCall
• Judith McConnell
• Anisha Nagarajan
• Evelyn Nesbit
• Sandra Dee Robinson
• Margot Rose
• Zelda Rubinstein
• Lillian Russell
• Rena Sofer
• Sam Sorbo
• Maddie Ziegler
• Chloe Lukasiak

• F. Murray Abraham
• Tom Atkins
• Carl Betz
• Christian Borle
• Don Brockett
• Steve Byrne
• Ted Cassidy
• David Conrad
• Maurice Costello
• Rusty Cundieff
• John Davidson
• Jack Dodson
• Charles Esten
• Patrick Fabian
• Joe Flaherty
• Scott Glenn
• Frank Gorshin
• Charles Grodin
• Kevin Peter Hall
• John Hodiak
• Michael Keaton
• Gene Kelly
• John Leslie
• Tom Major-Ball
• Joe Manganiello
• Jim Martin
• Kiel Martin
• Adolphe Menjou
• Kermit Murdock
• Burt Mustin
• Manu Narayan
• Bill Nunn
• Michael Park
• Billy Porter
• William Powell
• Zachary Quinto
• Fred Rogers
• Johnny Sins
• Jimmy Stewart
• Regis Toomey
• Fritz Weaver

• Marty Allen
• Steve Byrne
• Patti Deutsch
• Billy Gardell
• Eddie Ifft
• Anthony Jeselnik
• Jesse Joyce
• Mario Joyner
• Maxine Lapiduss
• Dennis Miller
• Frank Nicotero

• Jodi Applegate – NBC's Later Today
• John Buccigross – host, SportsCenter on ESPN
• Bill Burns – KDKA anchor (1953–1989)
• Patti Burns – KDKA anchor with her father Bill
• Bill Cardille – broadcaster known as Chilly Billy, host of Chiller Theatre and Studio Wrestling
• Murray Chass – sportswriter
• Beano Cook – ESPN college football analyst
• Myron Cope – sports journalist, radio personality, and sportscaster
• Scott Ferrall – sports talk radio host
• Howard Fineman – Newsweek journalist
• Fred Honsberger – broadcaster
• Sue Kerr – LGBTQ writer
• Jay Mariotti – sportswriter
• Jeanne Moos – CNN reporter
• Art Pallan – broadcaster
• Jim Quinn – radio talk show host
• Martha Rial – 1998 Pulitzer Prize for Spot News Photography
• Rick Sebak – WQED documentarian
• Paul Shannon – host of WTAE-TV children's show Adventure Time
• John Stehr – anchorman at WTHR in Indianapolis, Indiana
• Bari Weiss – opinion writer and editor

• Porky Chedwick – announcer
• Foo Conner – journalist
• Rege Cordic – actor and broadcaster
• Bill Cullen – TV game show host
• John Dennis – radio host
• Frank DiLeo – Michael Jackson's manager, Goodfellas cast member
• Phil Frank – cartoonist
• Chris Garver – tattoo artist, Miami Ink
• Justine Ezarik (aka. iJustine) – YouTube personality
• Rafe Judkins – Survivor: Guatemala
• Sarah Kozer – Joe Millionaire
• Billy Mays – television direct-response advertisement salesperson
• Sheena Monnin – Miss Pennsylvania
• Jenna Morasca – reality show contestant, winner of Survivor: The Amazon
• Sharon Needles – drag queen, winner of season four of RuPaul's Drag Race
• David Newell – TV actor, "Mr. McFeely" on Mister Rogers' Neighborhood
• Beth Ostrosky – model, TV personality, wife of Howard Stern
• Bob Trow – TV actor, "Bob Dog" and "Robert Troll" on Mister Rogers' Neighborhood
• Ricki Wertz – WTAE-TV
• Lucian Wintrich – Artist, writer, photographer, former White House Correspondent for Gateway Pundit

• Antoine Fuqua – director
• John P. Harris – invented the first movie theater
• David Hollander – TV and movie producer, director
• Tim Kaiser – producer, Seinfeld, Will & Grace, 2 Broke Girls
• Carl Kurlander – film producer, writer
• Sally Lapiduss – producer
• Rob Marshall – director, Chicago
• Greg Nicotero – actor, director, producer, special effects and makeup artist The Walking Dead
• Eric Red – screenwriter and director
• Ford Riley – producer, screenwriter and lyricist; created The Lion Guard
• George A. Romero – director, best known for Night of the Living Dead
• Richard Rossi – director
• Tom Savini – actor, stunt man, director, special effects and makeup artist
• Lou Scheimer – animator, voice actor, co-founder of animation studio Filmation
• David O. Selznick – film producer, Gone with the Wind
• Lewis J. Selznick – film producer
• Myron Selznick – producer, talent agency head

• Ray Anthony – bandleader
• Ron Affif – jazz guitarist
• Ron Anthony – jazz guitarist, teacher; Sinatra's guitarist for 10 years
• Bob Babbitt – bass player for Motown house band the Funk Brothers
• Sheryl Bailey – jazz guitarist^[1]
• George Benson – jazz guitarist, singer
• Harold Betters – jazz trombonist
• Art Blakey – jazz drummer, bandleader
• Ray Brown – jazz double bassist
• Paul Chambers – bass player
• Sonny Clark – jazz pianist
• Kenny Clarke – jazz drummer
• Johnny Costa – jazz pianist
• Frank Cunimondo – jazz pianist
• Johnny Daye – soul singer
• Billy Eckstine – singer
• Roy Eldridge – trumpeter
• Joel Forrester – pianist
• Barry Galbraith – jazz guitarist
• Erroll Garner – jazz pianist
• Walt Harper – jazz pianist
• Earl Hines – jazz pianist
• Roger Humphries – drummer
• Phyllis Hyman – singer
• Ahmad Jamal – jazz pianist
• Eddie Jefferson – singer, composer; wrote the lyrics to "Moody's Mood for Love"
• Dodo Marmarosa – be-bop pianist
• Billy May – bandleader, arranger for Frank Sinatra
• Sammy Nestico – arranger for Count Basie Orchestra
• Horace Parlan – pianist
• Leo Pellegrino – baritone saxophonist
• Jimmy Ponder – guitarist
• Billy Price – singer
• Eddie Safranski – bassist
• Shanice
• Dakota Staton – vocalist
• Billy Strayhorn – composer, pianist
• Maxine Sullivan – jazz vocalist
• Stanley Turrentine – tenor saxophone player
• Tommy Turrentine – trumpeter
• Mary Lou Williams – jazz pianist
• Spanky Wilson – jazz vocalist

• Loren Allred – singer
• Lory Bianco – singer
• Jackie Evancho – singer
• Colyn Fischer – fiddler
• Stephen Foster – 19th-century songwriter
• Philip Glass – composer
• Byron Janis – pianist
• Oscar Levant – pianist
• Lorenzo Malfatti – Italian opera coach
• Mary Lou Metzger – singer
• Mildred Miller – opera singer
• Joe Negri – musician, professor, best known as "Handyman Negri" on Mister Rogers' Neighborhood
• Leo Robin – lyricist

• Tunde Adebimpe – musician and actor, lead singer of TV on the Radio
• Bobby Blotzer – drummer for Ratt
• Ceann – Irish drinking music rock band
• William Fitzsimmons – musician
• Girl Talk – musician, real name Gregg Gillis
• Gramsci Melodic – alternative rock band
• Joe Grushecky – Iron City Houserockers, solo artist; worked with Bruce Springsteen
• Donnie Iris – musician
• Ray Luzier – Korn member
• Jerry Mason – singer
• Weird Paul Petroskey – lo-fi musician
• Justin Sane – lead guitarist and co-singer/songwriter of the political punk rock band Anti-Flag
• Spike Slawson – singer for Me First and the Gimme Gimmes

• Victor Herbert

• Eric Andersen
• Gabby Barrett
• Bill Deasy
• Guaranteed Irish
• Dan Levenson^[2]

• Tunde Adebimpe – singer, TV on the Radio
• Michele Brourman – composer
• Lou Christie – pop singer, "Lightning Strikes"
• Perry Como – crooner
• Daya – pop singer/songwriter
• The Del-Vikings – vocal group, Come Go With Me
• Jerry Fielding – Oscar-nominated composer
• Chris Jamison – singer-songwriter, musician, and contestant from NBC's The Voice season 7
• The Marcels – vocal group, "Blue Moon"
• The Skyliners – vocal group, Since I Don't Have You
• Jack Stauber - synth-pop singer-songwriter/instrumentalist
• B. E. Taylor – musician
• Bobby Vinton – pop singer, "Blue Velvet"
• Brian Young – drummer and percussionist, Fountains of Wayne

• Beedie – rapper
• Grand Buffet – rap duo
• Jasiri X – artist, activist, rapper, entrepreneur
• Jero
• Wiz Khalifa
• Lady Miss Kier – Deee-Lite
• Mel-Man – hip hop producer and rapper
• Pittsburgh Slim – rapper
• Mac Miller – rapper
• Chevy Woods – rapper
• Jimmy Wopo – rapper

• Kyle Abraham – choreographer
• Martha Graham – dancer and choreographer; awarded Presidential Medal of Freedom
• Billy Hartung – Broadway actor, dancer and singer
• Gene Kelly – iconic Hollywood dancer, actor, singer, director, and choreographer
• Chloe Lukasiak – actress and former featured dancer on TV show Dance Moms
• Abby Lee Miller – former dance studio owner, choreographer and team coach for Abby Lee Dance Company; featured on TV show Dance Moms
• Paul Taylor – choreographer
• Jonathan Wolken (1949–2010) – founder of the Pilobolus dance company^[3]
• Maddie Ziegler – actress and former featured dancer on TV show Dance Moms
• Mackenzie Ziegler – singer

• Matt Baker – comic book artist
• Romare Bearden
• Martin Beck – painter
• Seddon Bennington
• Sharif Bey – sculptor, ceramist, educator
• Ailsa Mellon Bruce – Mellon heir and art patron
• Norman Daly — visual artist
• Vanessa German – sculptor, poet
• David Hanna – artist
• Charles "Teenie" Harris – photographer
• Jerry Harris – sculptor
• Yvonne Jacquette – painter and printmaker
• Henry Koerner – painter
• Michael Lotenero – painter and sculptor
• Scott McDaniel – comic book artist
• James Michalopoulos – painter and sculptor^[4]
• Burton Morris – artist
• Thaddeus Mosley – sculptor
• Sharon Needles – drag queen, winner of RuPaul's Drag Race season 4
• Jackie Ormes
• Philip Pearlstein – painter
• Sara Penn – designer and curator
• Robert Qualters – painter
• Lawrence Saint – stained glass artist
• Naomi Sims – model
• George Sotter – painter
• Jack Stauber - animator
• Renee Stout – multi-media artist
• Andy Warhol – painter
• Julia Warhola

• Joseph Bathanti – poet, writer, professor; NC Poet Laureate, 2012–2014
• Nellie Bly – Pulitzer Prize-winning investigative journalist and writer
• Kenneth Burke – literary theorist
• Rachel Carson — marine biologist, writer, and conservationist
• Willa Cather – author, Pulitzer Prize winner
• Michael Chabon – Pulitzer Prize-winning author
• Murray Chass – New York Times baseball writer, author
• Stephen Chbosky – author
• Malcolm Cowley – poet, critic
• Melanie Craft – novelist; wife of Larry Ellison of Oracle
• Stephen Dau – writer
• Annie Dillard – author and Pulitzer Prize winner
• Harry Dolan – writer
• Zak Ebrahim – author, peace activist, public speaker
• Jack Gilbert – poet
• Lester Goran – writer and professor
• Beth Gylys – poet and professor
• George Heard Hamilton – art historian
• Kerry Hannon – author
• Agatha Tiegel Hanson – writer, poet, and editor
• Samuel Hazo – poet and professor
• Lori Jakiela – author
• George S. Kaufman – humorist, playwright
• Joseph Koerner – art historian
• David Leavitt – novelist
• Stephen Manes – magazine writer, author
• David McCullough – historian and author and two-time Pulitzer Prize winner
• Elizabeth Moorhead – novelist
• Burton Morris – painter
• Stewart O'Nan – author
• Peter Oresick – poet
• Mary Roberts Rinehart – mystery writer
• William Roos – playwright, mystery novelist, and screenwriter
• Gladys Schmitt – writer
• Jim Shooter – comic book writer, editor and publisher
• Michael Simms – poet in Pittsburgh since 1987
• George Smith – gambler, handicapper
• Gertrude Stein – writer, poet, playwright, and feminist
• Gerald Stern – poet
• Kathleen Tessaro – novelist
• John Edgar Wideman – author and professor
• August Wilson – Pulitzer Prize-winning playwright
• Cecilia Woloch – poet and writer
• Damon Young (writer) – author and columnist

• Glenn Beckert – second baseman
• Buddy Bell – third baseman (1972–1989)
• Bill Blair
• Dave Bush^[5]
• Ollie Carnegie – 1931–1945
• Betty Jane Cornett (1932–2006) – third base (1950–1952) All-American Girls Professional Baseball League
• Bill Doak – Cardinals and Dodgers, inventor of the modern baseball glove
• Ryan Garko – first baseman, Giants
• Josh Gibson – Negro league player, Pittsburgh Crawfords and Homestead Grays
• Gary Green
• Howdy Groskloss – shortstop 1930–32
• Ian Happ – Chicago Cubs
• Art Howe – managed Astros and A's
• Derek Law – pitcher
• Bobby Lowe – first MLB player with 4 home runs in a game^[6]
• Sam McDowell
• Marguerite Pearson – utility player 1948–1954, All-American Girls Professional Baseball League
• Heinie Smith^[6]
• Trent Thornton – pitcher for the Toronto Blue Jays
• Harold Joseph "Pie" Traynor – Pirates Hall of Fame member
• Honus Wagner – shortstop, Hall of Fame member
• Neil Walker – former MLB second baseman
• Bobby Wallace – Hall of Fame inductee^[6]
• John Wehner – Pirates infielder, broadcaster
• Josh Wilson – 2005–present

• Bill Benswanger – Pirates owner, vocal advocate for integration
• Chuck Greenberg – Rangers former owner
• Gus Greenlee – Crawfords founder
• John P. Harris – Boston Braves owner
• Ray Kennedy – scout and GM
• Tony LaCava – longtime scout and assistant general manager

• Dick Bennett – Wisconsin, Washington State 1976–2006
• Paul Birch
• Eddie Cameron – Duke 1929–1949 until 1972, Cameron Indoor Stadium, founding member of the ACC, football coach and Olympic selector
• Suzie McConnell-Serio – WNBA player 1998–2000, head coach 2004–2006, Duquesne 2007–2013
• Dudey Moore
• Skip Prosser – Loyola (MD), Xavier, and Wake Forest 1993–2007
• Herb Sendek – NC State and Arizona State 1994–2015

• John Abramovic – 1946–1948
• DeJuan Blair – Pitt All-American, Spurs 2009–2013, Mavericks 2013–2014
• Chuck Cooper – 1950–1956; first drafted African-American
• Jakim Donaldson (born 1983) – player in the Israeli Basketball Premier League
• Ken Durrett – 1971–1975 NBA
• Paul Grant – 1997–2004
• Maurice Lucas – 1975–1988
• Walt Miller – 1946–47
• Maurice Stokes – Rochester/Cincinnati Royals 1955–1958; Hall of Famer
• Walt Szczerbiak – 1971–72 NBA
• Michael Young (born 1994) – Ironi Nahariya of the Israeli Basketball Premier League

• Moe Barr – 1970–71 NBA
• Paul Birch
• Ron Carter – 1978–1980 NBA
• Calvin Fowler – 1969–70
• DeAndre Kane
• T. J. McConnell – Arizona Wildcats and Philadelphia 76er and Indiana Pacers
• Jack Twyman – 1955–1966, Hall of Famer

• Mark Cuban – Mavericks owner
• Tim Grgurich – Pitt coach
• Ted Stepien – Cavs former owner

• Bob Baker – heavyweight contender
• Eddie Chambers – Heavyweight and Cruiserweight Contender, 2008–2016
• Billy Conn – light-heavyweight champ 1939–1941
• Andy DePaul – middleweight contender, referee
• Harry Greb – middleweight champ 1923
• Frank Klaus – middleweight champ 1904
• Paul Spadafora – lightweight champ, 1999
• Jackie Wilson – featherweight champ, early 1900s (decade)
• Teddy Yarosz – middleweight champ, 1934
• Fritzie Zivic – welterweight champ, 1940

• Michael Seibert – five-time gold medalist at U.S. Figure Skating Championships; three bronze medals at World Championships
• Jamie Silverstein – ice dancing
• Taylor Toth – pairs skating

• Joe Bugel – assistant and head coach 1975–present; founder of the "Hogs" of the 1980s
• Jim Haslett – head coach Saints (2000–2005), Rams D.C. (2006–08)
• Mike McCarthy – Packers head coach 2005–2018
• Herb McCracken – college 1920s and 1930s
• Mike Miller – assistant 1999–present
• Dick Nolan – head coach, San Francisco 49ers and New Orleans Saints

• Joseph H. Thompson - University of Pittsburgh – 1909-1912
• Frank Cignetti, Jr. – University of Pittsburgh
• Tom Davies – 1922–1947
• Rich Lackner – Carnegie Mellon 1986–present

• Marc Bulger – 2000–2011, Super Bowl^[7]
• Chuck Fusina – NFL 1979–1986
• Bruce Gradkowski – Steelers, Bucs, Raiders 2006–2016
• Major Harris – record-setter in college and CFL
• Leon Hart – Heisman Trophy, College Hall of Fame
• Al Jacks – quarterback, Penn State and college head coach
• Jim Kelly – 1986–1996, Hall of Fame, 4 Super Bowl appearances
• Dan Marino – 1983–1999, Hall of Fame 1 Super Bowl appearance
• Mike McMahon – NFL, CFL, UFL quarterback 2001–2012
• Joe Namath – New York Jets, Alabama Crimson Tide National Champion
• Rod Rutherford – NFL quarterback 2004–2006 and college coach
• Matt Schaub – NFL quarterback 2004–2020
• Willie Thrower – first black quarterback in the NFL*
• Johnny Unitas – 1956–1973, Hall of Famer, two Super Bowls
• Alex Van Pelt – 1995–2003
• Scott Zolak – 1991–1999, 1 Super Bowl appearance

• Kevan Barlow – NFL running back 2001–2007
• Larry Brown – running back, Washington Redskins 1969–1976
• Tony Dorsett – NFL, HOF, Dallas Cowboys, University of Pittsburgh
• Cookie Gilchrist – AFL and CFL
• Warren Heller – NFL halfback 1930s
• William F. Knox – Yale and Carnegie Tech halfback
• Roger Kochman – 1963
• Curtis Martin – 1995–2006, HOF,

Super Bowl

• Harry McChesney – 1900s, NFL
• Eugene "Mercury" Morris – 70s Dolphins; two Super Bowls
• Vinnie Sunseri – NFL player and coach
• Ray Zellars – Saints

• Brian Baschnagel – originally a running back, Ohio State, Bears 1976–1984
• Darnell Dinkins – NFL tight end in the 1990s and 2000s (decade)
• John Frank – NFL tight end in the 1980s
• Gregg Garrity – Penn State, NFL 1983–1989
• Ken Herock – NFL tight end 1963–1969, Super Bowl
• Brandon Marshall – NFL wide receiver 2006–2018
• Rasheed Marshall – NFL wide receiver 2005–2007
• Joel Williams – NFL tight end, 1987

• Adam Bisnowaty – NFL offensive linesman for the New York Giants
• Dean Caliguire – NFL lineman in 1991
• Bill Fralic – offensive lineman for Atlanta Falcons, '80s All-Decade Team
• Gary Greaves – tackle 1960
• Leander Jordan – offensive lineman, Carolina Panthers, San Diego Chargers, Atlanta Falcons, Jacksonville Jaguars
• Mose Lantz – NFL center 1933
• William R. Moore – NFL guard in the 1940s
• Bull Polisky – NFL guard 1929
• Tom Ricketts – NFL tackle 1980s and 1990s
• Mike Rosenthal – NFL tackle 1999–2007
• Jack Sack – NFL guard in the 1920s

• Mike Barnes – pro bowler 1973–1981
• Bob Buczkowski – NFL defensive end in the 1980s
• Sam Clancy – NFL defensive end in the 1980s and 1990s
• Ave Daniell – NFL tackle in the 1930s
• Aaron Donald – NFL defensive tackle
• Jack Dugger – NFL lineman 1946–49
• Art Gob – NFL defensive end, 1950s and 1960s
• Cameron Heyward – NFL 2011–present
• Tyrique Jarrett – NFL defensive tackle
• David Logan – defensive tackle 1970s and 1980s
• Leo Skladany – NFL defensive end 1940s and 1950s
• Jason Taylor – defensive end; five-time Pro Bowler for Miami Dolphins
• Randy White – defensive lineman 1975–1988; three Super Bowls, Hall of Fame

• LaVar Arrington – NFL linebacker 2000–2006
• Jack Butler – cornerback 1951–1959, Pro Football Hall of Fame
• Jim Flanigan Sr. – NFL linebacker 1960s and 1970s
• Don Graham – Penn State, NFL 1987–1989
• Bobby Grier – Pitt Panthers 1952–1956, Hall of Famer, civil rights icon
• Justin King – NFL 2008–2012
• Nick Kwiatkoski – linebacker for the Atlanta Falcons
• Sean Lee – former linebacker for Dallas Cowboys
• Mike Logan – NFL safety 1996–2006, Super Bowl
• Paul Martha – NFL safety in the 1960s
• Dick McCabe – NFL safety in the 1950s and 1960s
• Ryan Mundy – NFL safety
• Paul Posluszny – Dick Butkus Award winner from Penn State, linebacker for Buffalo Bills
• Scott Radecic – Penn State and NFL linebacker 1984–1995
• Bryant Salter – NFL safety in the 1970s
• Joe Schmidt – linebacker 1953–1965, Hall of Fame
• Raymond Ventrone – safety, Cleveland Browns
• Eric Wicks – safety, finalist for Bronko Nagurski Award in 2007

• Pat McAfee – All Pro NFL punter, 2010's all decade team
• Don Silvestri – kicker in the 1990s

• Dave Berry – pro football pioneer
• Kevin Colbert – director of football operations (2 Super Bowls)
• Dale Hamer – NFL referee 1978–2001, 3 Super Bowls
• Shaun Herock – NFL executive
• Bill Nunn – Steelers scout since 1967
• Art Rooney – owner and founder of Pittsburgh Steelers Duquesne University
• Dan Rooney – second chairman of the Pittsburgh Steelers, member of the Pro Football Hall of Fame

• Scott Dunlap – PGA and Champions Tour
• Bob Friend – PGA and Nationwide Tour
• Jim Simons – as an amateur nearly won 1971 U.S. Open; first tournament winner using a metal driver
• Brendon Todd – PGA Tour
• Arnold Palmer – PGA Tour

• Riley Barber – Capitals winger, 2017–
• Ryan Malone – Penguins, Lightning, Rangers winger 2003–2015; 2017
• Gerry O'Flaherty – Leafs, Canucks, Flames 1971–1979
• Brandon Saad – Colorado Avalanche winger 2011–
• Henrik Samuelsson – Coyotes winger 2014–
• William Thomas – Anyang Halla winger 2005–
• Vincent Trocheck – Panthers 2014–2020, Hurricanes 2020–2022, Rangers 2022–
• R. J. Umberger – Flyers, Jackets center 2005–

• Matt Bartkowski – Iowa Wild
• Bob Beers – Bruins, Lightning, Oilers, Islanders defenseman 1989–1997
• Dylan Reese – Rangers, Islanders, Penguins 2007–
• Mike Weber – former NHL defenseman.

• John Gibson – player for Anaheim Ducks

• James Wallace Conant – managed Duquesne Gardens

• Kurt Angle – 1996 gold medalist in freestyle wrestling, later became a professional wrestler
• Robert "Bob" Blum (born 1928) – Olympic fencer
• Herb Douglas – long jump bronze medalist at 1948 Summer Olympics; inducted into Pennsylvania Sports Hall of Fame 1992
• Michael Grady – rower and gold medalist
• Jake Herbert – folkstyle and freestyle wrestler, 2009 world silver medalist, represented USA at 2012 Summer Olympics
• Suzie McConnell-Serio – basketball 1988 and 1992
• Allison Schmitt – competitive swimmer, four time Olympian^[8]
• Leah Smith – swimming, gold and bronze medalist in 2016 Olympics
• Amanda Polk – rowing, gold medalist W8+ in 2016 Olympics

• Meghan Klingenberg – player for the Portland Thorns FC and United States women's national soccer team
• A. J. Wood – MLS player
• Marvell Wynne II
• David Tepper owner of the MLS's Charlotte FC

• Bjorn Fratangelo – French Open boys' champion^[9]
• Bonnie Gadusek – pro tennis player, reached U.S. Open quarterfinals
• Gretchen Magers – reached Wimbledon and French Open quarterfinals
• Alison Riske – WTA player, reached 4th round of U.S. Open

• Kurt Angle – WWE/TNA wrestler and Olympic gold medalist
• Britt Baker – AEW wrestler
• Rob Conway – WWE wrestler on RAW brand
• Johnny De Fazio – known as "Jumping" Johnny De Fazio
• Dominic DeNucci – WWWF wrestler and trainer
• Shane Douglas – ECW, WCW, and WWF wrestler
• Corey Graves – wrestler, WWE commentator
• Mike Jones – known as Virgil in WWE; worked as Vincent, Shane and Curly Bill in WCW
• Cody Michaels – former USWA tag team champion, ECW, WSX producer
• John Minton – WWF aka Big John Studd
• Bruno Sammartino – two-time World Wide Wrestling Federation champion
• Mike Scicluna – known as Baron Mikel Scicluna
• Jeffrey Sciullo – WWE wrestler known as Ezekiel (formerly Elias (Samson))
• John Sullivan – known as Johnny Valiant
• Newton Tattrie – known as Geeto Mongol
• Larry Zbyszko (real name Larry Whistler) – director of authority on Total Nonstop Action Wrestling

• Danny Chew – cyclist, winner of Race Across America (1996, 1999)
• Joseph Kearney – athletic administrator
• George Smith – horse racing
• Tom Wallisch – professional skier

• Paige Kassalen – electrical engineer on Solar Impulse
• Willard Rockwell – formed Rockwell Intl.
• Calbraith Perry Rodgers – made the first transcontinental flight

• James W. Brown – Crucible Steel
• Andrew Carnegie – steel tycoon and philanthropist, founded what became U.S. Steel
• William Donner – steel tycoon, founded Monessen and Donora, daughter married FDR's son in 1932
• George Washington Gale Ferris Jr. – steel engineer, businessman and inventor of the Ferris wheel
• Henry Clay Frick – steel tycoon, chief operation officer of what became U.S. Steel
• Charles Martin Hall – aluminum producer and founder of Alcoa
• Julian Kennedy – mechanical engineer in steel
• George Lauder – Scottish-American billionaire industrialist; partner in the Carnegie Steel Company; board member of U.S. Steel; cousin-brother of Andrew Carnegie
• James H. Laughlin – Jones & Laughlin Steel
• John Leishman – executive at Carnegie Steel
• William Metcalf – Fort Pitt foundry
• Charles M. Schwab – founder of Bethlehem Steel
• John P. Surma – U.S. Steel
• Thomas Usher – CEO of U.S. Steel and chairman of the board of Marathon Oil
• John Walker – iron and steel industrialist

• Walter Arnheim – Mobil executive and corporate and non-profit advisor
• Frederick Bausman
• E. W. Marland – oilman, founded what would become Conoco, also became the governor of Oklahoma
• William Mellon – co-founded Gulf Oil

• Erik Buell – Buell Motorcycle Company
• Alexander Cassatt – Pennsylvania Railroad
• Louis Semple Clarke – steamboats
• John E. Connelly – Gateway Clipper Fleet
• Mike Fink – river boatman
• Robert Pitcairn – Pennsylvania Railroad
• Samuel Rea – Pennsylvania Railroad

• John F. Donahue – chairman, Federated Investors
• Stanley Druckenmiller – hedge fund manager
• Thomas Marshall Howe – 19th-century politician
• James Lindenberg – founder of ABS-CBN Corporation
• Richard B. Mellon – banker, philanthropist
• Thomas Mellon – founded Mellon Financial
• David Tepper – businessman, hedge fund manager, philanthropist, and owner of the Carolina Panthers
• William Thaw – 19th-century banker

• Luis von Ahn – CAPTCHA inventor, Duolingo founder
• William Bullock – printing press innovator
• Charlie Cheever – co-founder of Quora
• Brendan Eich – Mozilla, creator of JavaScript
• Caterina Fake – co-founder of Flickr and Hunch
• John P. Harris – theater owner
• Regis McKenna – high technology marketing guru
• Willard Rockwell – pioneer of Rockwell Intl.
• Richard Mellon Scaife – Tribune-Review
• Rich Skrenta – computer programmer
• George Westinghouse – electrical industry pioneer
• Mark Whitaker – CNN Worldwide chief^[10]
• Jamie Zawinski – hacker

• Peter Chartier (Chartiers Town and Tarentum) – fur trader 1734–1743
• David L. Clark
• H. J. Heinz II – CEO of H.J. Heinz Co.
• Henry J. Heinz – founder of H. J. Heinz Company
• Edgar J. Kaufmann – Kaufmann's
• Billy Mays – TV pitchman
• James Sinegal – Costco
• Patricia A. Woertz – ADM^[11]

• William D. Boyce – founder of Boy Scouts of America
• Dr. Herbert Boyer – co-founder of Genentech
• John Baptiste Ford – PPG Industries
• Ed Grier – Disneyland
• Joseph A. Hardy III – 84 Lumber
• Bob Stupak – Vegas Stratosphere

• David J. McDonald – president of steelworkers union
• Theodore Schaffer – president of the Amalgamated Association of Iron, Steel, and Tin Workers
• Fannie Sellins – union organizer
• John Sheridan Weller – attorney and politician
• Joseph Yablonski – UMW

• Catherine Anne Cesnik (1942–1969) – Catholic nun who was murdered
• Cardinal Daniel DiNardo – archbishop of Galveston-Houston
• Thomas Dolinay – archbishop
• Joseph R. Lamonde
• Cardinal Adam Maida – Emeritus Archbishop of Detroit
• Lippman Mayer – rabbi
• Janice McLaughlin – Catholic nun and human rights activist
• Madalyn Murray O'Hair – founder of American Atheists
• William Passavant
• George Rapp – founder of the religious sect Harmonists
• Charles Owen Rice
• Charles Taze Russell – founder of Watch Tower Bible & Tract Society
• R. C. Sproul – theologian
• Thomas J. Tobin – auxiliary bishop of Pittsburgh, bishop of Youngstown OH, and current bishop of Providence, Rhode Island
• Cardinal Donald Wuerl – eleventh bishop of the Roman Catholic Diocese of Pittsburgh, current Archbishop of Washington
• David Zubik – twelfth and current bishop of the Roman Catholic Diocese of Pittsburgh

• Ross Allen – herpetologist
• Frederick S. Billig – scramjet pioneer
• Daniel Chamovitz – biologist, author of What a Plant Knows, and President of Ben Gurion University of the Negev^[12]
• Yuan Chang – virologist, co-discoverer of causes of several viral cancers, including Kaposi's sarcoma
• Norman Christ – physicist
• Childs Frick
• George Otto Gey – scientist who propagated the HeLa cell line
• William Jacob Holland – entomologist and chancellor of the Western University of Pennsylvania
• Irene Jakab (1919–2011) – native of Hungary, psychiatrist and humanist; member of the faculties of Harvard University, the University of Pittsburgh and the McLean Hospital
• Ayana Jordan – addiction psychiatrist
• Randy Pausch – founder of Alice, and man behind the Last Lecture
• David M. Pozar – electrical engineer and academician^[13]
• Jonas Salk – physician, inventor of first polio vaccine
• Alex Shigo – arboriculturist and horticulturist
• Clifford Shull – Nobel Prize winner
• Herbert A. Simon – Carnegie Mellon University professor; winner of Nobel Prize for Economics
• Thomas Starzl – pioneering transplant surgeon in liver and multiorgan transplantation
• Jesse Steinfeld – United States Surgeon General under Nixon
• Otto Stern – German-American physicist and Nobel laureate, known for his studies of molecular beams; Carnegie Institute of Technology professor
• Nicholas E. Wagman
• Sandra Welner (1958–2001) – physician, advocate for disabled women's healthcare
• Jerome Wolken (1917–1999) – biophysicist^[14]
• Jamie Zawinski
• Jonathan Zittrain – professor of Internet law and computer science at Harvard
• Vladimir Zworykin – engineer and inventor, developed an early form of television; the IEEE presents a Vladimir Zworykin Award for outstanding contributions to development of television technology

• Ebenezer Denny – 10th Adjutant General of the U.S. Army

• John M. Corse
• Benjamin Grierson – Civil War and Buffalo Soldier
• Alexander Hays – Brigadier General*, repulsed Pickett's Charge at Gettysburg
• Francis J. Herron
• Alexander Murray – Admiral
• James Scott Negley – Major General Civil War hero of Murfreesboro
• Thomas A. Rowley (1808–1892) – Brigadier-general; Gettysburg; Civil War
• Jacob B. Sweitzer – General* Civil War, led major offensives at Gettysburg
• Samuel Baldwin Marks Young

• Joseph R. Lamonde
• Manus MacCloskey – Brigadier General
• Samuel Baldwin Marks Young – first Chief of Staff of the Army

• Michael Hayden – USAF ****, Director of NSA, CIA
• Harry E. Miller Jr. – major general who commanded the 42nd Infantry Division^[15]

• Charles Higby
• Alexander Kelly
• Alfred L. Pearson – Medal of Honor
• James Schoonmaker

• Charles Bishop
• Robert Semple

• Joseph H. Thompson — Medal of Honor

• Arthur V. Ely
• Charles E. Kelly
• Archibald Mathies

• William D. Morgan
• William R. Prom

• Jay Apt – astronaut and professor
• Mike Fincke – Colonel, United States Air Force
• Terry Hart – Lieutenant Colonel, United States Air Force
• James Irwin – Apollo Lunar Module pilot of Apollo 15 and eighth person to walk on the Moon

• Thomas Enright - first soldier from Pennsylvania, and possibly first American soldier, killed in World War I
• Adrian Cronauer – Airman, radio personality, subject of Good Morning, Vietnam
• Charles Graner – U.S. Army reservist convicted of prisoner abuse in connection with 2003–2004 Abu Ghraib prisoner abuse scandal

• Bob Cranmer – Allegheny County Commissioner
• Justin Fairfax – Lieutenant Governor of Virginia
• Bob Filner – San Diego Mayor
• John F. Forward Sr. – 12th mayor of San Diego
• John F. Forward Jr. – 21st mayor of San Diego
• Barbara Hafer – first female Allegheny County Commissioner
• E. W. Marland – Governor of Oklahoma
• Elliot S. N. Morgan – Wyoming governor
• Janet Napolitano – Arizona governor
• Tom Ridge – Governor 1995–2001; first Secretary of Homeland Security
• John K. Tener – Governor, former MLB pitcher
• Dick Thornburgh – Governor 1979–1987; U.S. Attorney General 1987–1991
• Tom Vilsack – Iowa Governor, 1999–2007; Agriculture Secretary, 2009–2017

• John Dalzell – Congressman 1887–1913; Chairman of the Ways and Means committee 1898–1913
• Harmar Denny – Congressman 1825–1837
• Bob Filner – California Congressman 1993–2012
• Orrin Hatch – Utah Senator, 1977–2019
• John Heinz – Congressman 1971–1977, Senator 1977–1991
• Thomas Marshall Howe – Congressman 1851–1855
• John Kasich – Ohio Congressman 1983–2001, Governor 2011–2019
• Philander C. Knox – Senator 1901–1904, 1917–1921, United States Attorney General 1901–1904, Sec. of State 1909–1913
• Robert McKnight – Congressman 1859–1863
• George T. Oliver – Senator 1909–1917
• Rand Paul – Kentucky Senator 2011–present, Tea Party leader
• Ron Paul – Texas Congressman, presidential candidate
• David A. Reed – Senator
• Rick Santorum – Congressman 1991–1995, Senator 1995–2007
• Claudine Schneider – Congresswoman Rhode Island 1981–1991

• Max Baer – Pennsylvania Supreme Court 2003–
• Derrick Bell – law professor
• Robert Bork – Supreme Court nominee, and acting AG
• George Dallas – Federal Court of Appeals 1892–1909
• Michael Fisher – Federal Appeals 2003–
• Albert Gordon – advocate for gay rights^[16]
• Ken Gormley
• Philip Heymann – served in Carter and Clinton administrations
• William G. Hundley – prosecutor and criminal defense attorney
• Linda Kelly – Pennsylvania Attorney General
• Rolf Larsen – State Supreme Court Justice
• Donald J. Lee – Federal 1989–2000
• Timothy K. Lewis – Federal 1991–1992, Appeals 1992–1999
• Carol Los Mansmann – Federal 1982–1985, Appeals 1985–2002
• Wilson McCandless – U.S. Judge
• Joan Melvin – Pennsylvania Supreme Court 2009–
• John Lester Miller – 1954–1971
• Michael Angelo Musmanno – PA Supreme Court and Nuremberg tribunal
• Arthur Schwab – U.S. Judge 2002–present
• George Shiras – U.S. Supreme Court
• Sara Soffel – first woman to serve as a judge in Pennsylvania
• William Alvah Stewart – Federal 1951–1953
• Hubert Irving Teitelbaum – 1970–1985
• W. H. Seward Thomson – Federal – 1914–1928
• Gerald Tjoflat – Appeals 1975–present
• Jay Waldman – Federal 1988–2003
• Joseph F. Weis, Jr. – Federal 1970–1973, Appeals 1973–1988
• James Scott Young – Federal 1908–1914
• Donald Emil Ziegler – Federal 1978–2003

• James J. Davis – Secretary of Labor under presidents Harding, Coolidge, and Hoover
• Walter Forward – United States Secretary of the Treasury under John Tyler, 1841–1843
• Albert Gallatin – Treasury Secretary
• Paul H. O'Neill – 72nd United States Secretary of the Treasury
• Edwin Stanton – Secretary of War under President Lincoln
• Judge William Wilkins – Secretary of War under President Tyler

• Homer S. Ferguson – Philippines
• Walter Forward – Denmark
• Mark Gilbert – New Zealand; also Major League Baseball player
• George W. Guthrie – Japan
• William W. Irwin – Denmark
• Andrew Mellon – Great Britain 1932–33
• Alexander Pollock Moore – Spain and Peru
• Dan Rooney – Ireland 2009–2012
• Edith S. Sampson – first African-American in the U.N. (1950–1953) and NATO (1961–62)
• Adolph W. Schmidt – Canada 1969–1974
• Phillips Talbot – Greece

• Paul P. Boswell – physician, member of the Illinois House of Representatives
• David Dank – member of the Oklahoma House of Representatives since 2007
• John R. Jones – member of the Wisconsin State Assembly
• Andrew P. Kealy – member of the Wisconsin State Assembly
• Emily Kinkead – member of Pennsylvania House of Representatives
• Alexander McDonald Thomson – Speaker of the Wisconsin State Assembly

• Euphemia Bakewell
• Lucy Dorsey Iams
• Jennie E. Kennedy
• Lucy Kennedy Miller
• Jennie Bradley Roessing
• Eliza Kennedy Smith
• Anne Steytler

• Rachel Foster Avery
• John Brabender
• Murray Chotiner
• Patrick R. Donahoe
• Tony Fratto – Deputy Press Secretary 2006–2009
• Elsie Hillman – former Republican National Committeewoman from Pennsylvania
• John Walker III – director, National Gallery of Art

• Vic Cianca – Pittsburgh traffic cop made famous by Johnny Carson, Candid Camera and Flashdance
• Thomas Delahanty – police officer who took a bullet in President Ronald Reagan's 1981 assassination attempt; declared a hero and awarded a medal for bravery

• Richard Baumhammers – spree killer
• Lawrence Bittaker – one of the two "Toolbox Killers"
• Connor Michalek – WWE fan and cancer victim