Lacidipine

Clinical data
Trade names	Lacipil, Motens
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	C08CA09 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	~10%
Protein binding	>95%
Metabolism	Hepatic
Onset of action	30–50 min
Elimination half-life	13–19 hours
Excretion	Feces (~70%)
Identifiers
IUPAC name Diethyl 4-{o-[(E)-2-tert-butoxycarbonylethenyl]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS Number	103890-78-4
PubChem CID	5311217
ChemSpider	4470736
UNII	260080034N
KEGG	D04657 Y
CompTox Dashboard (EPA)	DTXSID1046429
ECHA InfoCard	100.166.373
Chemical and physical data
Formula	C26H33NO6
Molar mass	455.551 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2/C=C/C(=O)OC(C)(C)C)C(=O)OCC)C)C
InChI InChI=1S/C26H33NO6/c1-8-31-24(29)21-16(3)27-17(4)22(25(30)32-9-2)23(21)19-13-11-10-12-18(19)14-15-20(28)33-26(5,6)7/h10-15,23,27H,8-9H2,1-7H3/b15-14+ Key:GKQPCPXONLDCMU-CCEZHUSRSA-N
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Lacidipine (tradenames Lacipil or Motens) is a calcium channel blocker. It is available as tablets containing 2 or 4 mg.

It was patented in 1984 and approved for medical use in 1991.^[1]

• Motens 2 mg Summary of Product Characteristics

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