L-serine-phosphatidylethanolamine phosphatidyltransferase

L-serine-phosphatidylethanolamine phosphatidyltransferase
Identifiers
EC no.2.7.8.29
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

L-serine-phosphatidylethanolamine phosphatidyltransferase (EC 2.7.8.29, phosphatidylserine synthase 2, serine-exchange enzyme II, PTDSS2 (gene)) is an enzyme with systematic name L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase.[1][2] This enzyme catalyses the following chemical reaction

L-1-phosphatidylethanolamine + L-serine L-1-phosphatidylserine + ethanolamine

This enzyme catalyses replacement of a polar head group of phosphatidylethanolamine with L-serine.

References

  1. ^ Stone SJ, Vance JE (August 1999). "Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2". The Biochemical Journal. 342 (1): 57–64. doi:10.1042/0264-6021:3420057. PMC 1220436. PMID 10432300.
  2. ^ Tomohiro S, Kawaguti A, Kawabe Y, Kitada S, Kuge O (March 2009). "Purification and characterization of human phosphatidylserine synthases 1 and 2". The Biochemical Journal. 418 (2): 421–9. doi:10.1042/bj20081597. PMID 19014349.