Clemons had recurring roles in numerous television series, including Austin & Ally (2013), Transparent (2014–2015), Extant (2015), and Easy (2016–2019), and had a main role in the final season of the comedy series Angie Tribeca (2018).
Early in her career, Clemons co-starred in the Disney Channel series Austin & Ally as Kira Starr. She also appeared in the Disney Channel original film Cloud 9. Clemons guest-starred in the crime-drama series CSI: Crime Scene Investigation. In 2014, she appeared in Trey Songz's music video for "SmartPhones" and "What's Best for You" in which she played his love interest who catches him in the act of cheating via phone call.
From 2014 to 2015, Clemons played Bianca in the comedy series Transparent.[3] She also had a starring role on the MTV original series Eye Candy as Sophia. The series only aired for one season.[4] She guest starred in a 2015 episode of New Girl as Winston's love interest, KC.[3] Clemons appeared in Lady Gaga's music video for "Til It Happens to You", and in DJ Snake's music video for "Middle" alongside Josh Hutcherson. In 2016, Clemons played Beth in the comedy film Neighbors 2: Sorority Rising. She also played Chase, a grad student from Chicago, in episodes of the Netflix original series Easy.[5]
In 2016, Clemons was cast as Iris West in the action film The Flash,[6] but the project was delayed due to the departure of director Rick Famuyiwa. Despite this, she was still slated to appear in the Justice League film as the same character,[7] but her scenes were ultimately cut from the theatrical release. In 2021, Clemons' cut scenes from the 2017 Justice League movie was eventually released in Zack Snyder's Justice League. In March 2021, Clemons closed a deal to appear as Iris West in The Flash, now directed by Andy Muschietti.[8]
Clemons identifies as queer.[11] She is in a relationship with Ebony De La Haye, an Australian stunt double.[12] The couple met during filming of Sweetheart, where De La Haye doubled Clemons during action sequences.[13]
Clemons suffers from bipolar disorder and struggled with the illness especially before she was formally diagnosed.[14]