Hudson attended McKeesport Area High School in Pennsylvania where he played safety and running back. He was recruited by several top programs as a two-way player.[1] At the time of his January 27, 2016 commitment to Michigan he was the number one rated football prospect in the Pennsylvania statewide class of 2016 according to Scout.com and the number 10 rated player on Rivals. He had offers from Pittsburgh, UCLA, and Penn State.[2]
Hudson made his debut on September 3, 2016, against Hawaii.[3] In the 2016 campaign, Khaleke made an appearance in all 13 games primarily on special teams. Khaleke only appeared in 2 games as a Safety, and was the Special Teams Player of the Game after a home win against Illinois.[4] On November 4, 2017, he set the school single-game record with eight tackles for loss against Minnesota in the Little Brown Jug rivalry game,[5] earning Big Ten Conference Co-Defensive Player of the week.[6] Hudson was recognized as the FWAA/Bronko Nagurski National Defensive Player of the Week for the effort (15 total tackles, 12 of which were solo, 3 quarterback sacks, and a forced fumble),[7] which tied an NCAA single-game record and set a Big Ten Conference tackle for loss record.[8][9] Following the 2017 season, Hudson, who was second in the conference in tackles for loss for the season, earned third-team All-Big Ten recognition from the coaches.[8][10]
Prior to his junior season in 2018, Hudson was named to preseason watch lists for the Lott Trophy and Bronko Nagurski Trophy.[11][12] He was named preseason first-team all-Big Ten by Athlon Sports.[13] Hudson appeared in all 13 games for the Wolverines but assumed a lesser role in the defense than his sophomore season. He finished with three tackles for loss and 39 total tackles on the year, and was named an honorable mention all-conference selection by both media and coaches.[14][15]
As a senior, Hudson was named to the preseason watchlist for the Butkus Award.[16] During the 2019 season, Hudson was Michigan's leading tackler with a career-best 97 stops, including 3.5 for loss with two sacks. He added three pass breakups, three quarterback hurries, and a blocked kick. In the following season Hudson was named to second-team 2019 All-Big Ten.[17]
On December 7, 2021, Hudson was placed on injured reserve after suffering an ankle injury in the Week 13 game against the Las Vegas Raiders.[22]
On August 30, 2022, Hudson was waived by the Commanders and signed to the practice squad the next day.[23][24] He was promoted to the active roster on October 21.[25] He signed a one-year contract extension on March 12, 2023.[26]
New Orleans Saints
On April 4, 2024, Hudson signed with the New Orleans Saints.[27] He was released on August 27, and re-signed to the practice squad.[28][29]
Cleveland Browns
On September 11, 2024, Hudson was signed by the Cleveland Browns off the Saints practice squad.[30]