Henry Pepwell (or Pepwall) (died 1539 or 1540) was an English printer.

Born in Birmingham, Pepwell set up business from 1518 at the former house of the stationer Henry Jacobi in St Paul's Churchyard, London. The first book he printed was William Neville's Castell of Pleasure. He was also involved with printing early English humanist works. In 1525-6 he was warden of the Company of Stationers.

• Alexandra Gillespie, ‘Pepwell , Henry (d. 1539/40)’, Oxford Dictionary of National Biography, Oxford University Press, 2004, accessed 25 Oct 2007

• Works by Henry Pepwell at Project Gutenberg
• Works by or about Henry Pepwell at the Internet Archive

• The Cell of Self-Knowledge : seven early English mystical treatises printed by Henry Pepwell in 1521 at Project Gutenberg