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Flumedroxone

This article is about a non-clinically used progesterone derivative. For the pharmaceutical drug, see flumedroxone acetate.
Flumedroxone
Skeletal formula of flumedroxone
Ball-and-stick model of the flumedroxone molecule
Clinical data
Other names17α-Hydroxy-6α-(trifluoromethyl)pregn-4-ene-3,20-dione; 6α-Trifluoromethyl-17α-hydroxyprogesterone
Identifiers
  • (2R,8S,14S,15S)-14-acetyl-14-hydroxy-2,15-dimethyl-8-(trifluoromethyl)tetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H29F3O3
Molar mass398.466 g·mol−1
3D model (JSmol)
  • CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H](C4=CC(=O)CC[C@]34C)C(F)(F)F)C)O
  • InChI=1S/C22H29F3O3/c1-12(26)21(28)9-6-16-14-11-18(22(23,24)25)17-10-13(27)4-7-19(17,2)15(14)5-8-20(16,21)3/h10,14-16,18,28H,4-9,11H2,1-3H3/t14-,15+,16+,18+,19-,20+,21+/m1/s1
  • Key:CDZJOBWKHSYNMO-SCUQKFFVSA-N
  (verify)

Flumedroxone is a steroidal progestogen of the 17α-hydroxyprogesterone group that was never marketed.[1] The C17α acetate ester of flumedroxone, flumedroxone acetate, has been marketed as an antimigraine drug.[1]

References

  1. ^ a b J Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 560–. ISBN 978-1-4757-2085-3.



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